Structures resembling Meissner corpuscles have been described in various nerve sheath tumors, including schwannomas and neurofibromas. When present, they are focal or scattered, and rarely a prominent feature of the lesion. Here, we report a case of a 39-year-old female who presented with an isolated lesion on her abdomen. Histopathologically, the tumor was almost exclusively composed of Meissner corpuscle-like structures (pseudo-meissnerian bodies). At a small edge of the tumor, there were features of a classic neurofibroma, with a mixture of Schwann cells, fibroblast-like cells, and interspersed mast cells. We propose the term "meissnerian neurofibroma" for this extremely rare variant of neurofibroma.
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http://dx.doi.org/10.1111/cup.13759 | DOI Listing |
Neuropathol Appl Neurobiol
October 2022
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Pediatric Oncology and Hematology, Berlin, Germany.
J Cutan Pathol
October 2020
ProPath Dermatopathology, Dallas, Texas, USA.
Structures resembling Meissner corpuscles have been described in various nerve sheath tumors, including schwannomas and neurofibromas. When present, they are focal or scattered, and rarely a prominent feature of the lesion. Here, we report a case of a 39-year-old female who presented with an isolated lesion on her abdomen.
View Article and Find Full Text PDFHistopathology
November 2001
Department of Pathology, Hospital Clínico Universitario, University of Valencia, Valencia, Spain.
Aims: A wide variety of differentiation patterns may be found in malignant melanoma. Schwannian features are unusual, and mostly present in the desmoplastic variant. We report the first description of psammoma bodies in malignant melanoma.
View Article and Find Full Text PDFCancer
August 1999
Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, USA.
Background: Neurofibroma of the urinary bladder is rare. Only isolated case reports have appeared. Information regarding the long term follow-up of patients with neurofibroma is limited.
View Article and Find Full Text PDFRom J Morphol Embryol
September 1995
Department of Morphopathology, University of Medicine and Pharmacy, Jassy, Romania.
17 cases of giant congenital nevi were reported. The lesions were located on the scalp, on the back and on the shoulders. The histopathological study revealed two cellular types of giant nevus; nevus cell type and neuroid type.
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