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Multimodality Approach to a Neonate With a Pericardial Mass and a Hemorrhagic Pericardial Effusion.
JACC Case Rep
December 2024
Icahn School of Medicine at Mount Sinai, Mount Sinai Kravis Children's Hospital, New York, New York, USA.
A 7-week-old infant with a 1-week history of a SARS-CoV2 respiratory infection presented with tachypnea. Cardiomegaly was noted on chest roentgenogram. Echocardiogram showed a large pericardial effusion, with tamponade physiology and a large pericardial mass.
View Article and Find Full Text PDFThe prevalence of in children in Shandong, China before, during, and after COVID-19.
Front Pediatr
December 2024
Department of Clinical Laboratory, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China.
Background: The multifaceted non-pharmaceutical interventions after the outbreak of the COVID-19 pandemic not only limited the spread of SARS-CoV2 but also had an impact on the prevalence of other pathogens.
Methods: In this work, we retrospectively analyzed the epidemiological characteristics of (MP) in children before and after the COVID-19 pandemic in Shandong, China. From 2019-2023, there were 29,558 visits of pediatric patients (1 month to 15 years old) with respiratory tract infection (RTI) symptoms at a tertiary hospital in Shandong Province, 10,039 of which were positive for MP according to a passive agglutination assay of the serum IgM antibodies.
Severe hypertransaminasaemia during the acute hepatitis of unknown origin alert of 2022.
An Pediatr (Engl Ed)
December 2024
Servicio de Bioquímica Clínica, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Introduction: The impact of acute severe hepatitis of unknown origin in children (SHIC) subject to a medical alert in 2022 medical alert is poorly understood.
Materials And Methods: Observational study of the incidence, aetiology and clinical presentation of acute hypertransaminasaemia (HTRA) with laboratory values in the severe range (ALT and/or AST ≥ 500 U/L) in paediatric patients (age 0 to 16 years) in one health care zone from 2012 to 2022, comparing the periods of the SHIC alert and the SARS-CoV2 pandemic with previous years.
Results: The incidence of severe HTRA of any cause was 195.
Features of chronic urticaria after COVID-19 mRNA vaccine over time.
Commun Med (Lond)
November 2024
Division of Immunology and Allergy, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Article Synopsis
- Chronic urticaria (CU) has been reported in some individuals after receiving the Moderna mRNA-1273 vaccine, prompting this study to analyze its onset related to COVID-19 vaccination, SARS-CoV-2 infection, and atopy factors.
- A study involving 50 individuals with CU and 135 without CU assessed the immunological responses and the presence of anti-vaccine IgE through surveys and blood tests conducted in 2022 and 2023.
- Results indicated that post-vaccination CU typically appears about 10 days after the Spikevax booster, especially affecting middle-aged women, with 53% of cases still active in 2023; however, some patients tolerated additional doses without worsening their symptoms,
How to Manage a Neonate Born from a SARS-CoV-2-Positive Mother: A Narrative Review.
Pathogens
November 2024
Neonatal and Pediatric Unit, Polo Ospedaliero Oltrepò, ASST Pavia, 27058 Voghera, Italy.
From 2020 to today, considerable knowledge on SARS-CoV-2 has been collected, even on pregnant women and their fetuses and newborns, and clinical guidelines have been written and implemented worldwide. Vaccination has considerably improved outcomes, but hesitancy amongst pregnant patients and the emergence of variants remain challenging, and SARS-CoV-2 positivity during pregnancy continues to be associated with an increased risk of maternal complications, premature delivery, and higher neonatal mortality and morbidity. A body of data now exists on the effect of SARS-CoV-2 during pregnancy on early neonatal outcomes, medical education in obstetrics and pediatrics, and longer-term developmental outcomes.
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