[Hospital experience in active immunoprophylaxis against HBV].

According to the Ministry of Health, at the paediatric section of Central Hospital of Rovigo, a vaccination campaign against HBV was undertaken in the year 1985 with the main purpose to reduce the sickness-rate and the mortality by HBV. Two vaccination patterns have been applied and they show to be efficient. 46 risk-subjects divided into two groups were vaccinated: group A: newborn, sons of women HBc Ag positive; group B: children living together with carriers or subjects sick of hepatitis B. The group A subjects had undergone to passive immunoprophylaxis at birth and to a vaccination cycle. The group B subjects only vaccination. The research of antibody titres produced by the vaccination demonstrated in the majority of cases greater than 121 IU/L. Only about 25% of vaccinated subjects showed a feeble movement of transaminases. The children's parents have cooperated very well.