Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673184 | PMC |
| http://dx.doi.org/10.1177/1932296820929368 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: The development and approval of novel drugs are typically time-intensive and expensive. Leveraging a computational drug repurposing framework that integrates disease-relevant genetically regulated gene expression (GReX) and large longitudinal electronic medical record (EMR) databases can expedite the repositioning of existing medications. However, validating computational predictions of the drug repurposing framework remains a challenge.
View Article and Find Full Text PDFAdvancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review.
Rev Cardiovasc Med
January 2025
Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine, Pain and Palliative Therapy, Asklepios Klinikum Harburg, 21075 Hamburg, Germany.
Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide, with a low survival rate of around 7% globally. Key factors for improving survival include witnessed arrest, bystander cardiopulmonary resuscitation (CPR), and early defibrillation. Despite guidelines advocating for the "chain of survival", bystander CPR and defibrillation rates remain suboptimal.
View Article and Find Full Text PDFThe Effectiveness of E-Learning Anticipatory Guidance on Early Childhood Caries among the Mothers of Children Aged 9-24 Months during the Pandemic: A Nonrandomized Controlled Trial.
Int J Clin Pediatr Dent
December 2024
Department of Pediatric and Preventive Dentistry, KVG Dental College and Hospital, Sullia, Karnataka, India.
Background: Early childhood caries (ECC) is a multifactorial disease with known etiologic factors and can be very devastating to the oral and general well-being of a child, including psychological impacts on a growing child. Young children constitute a vulnerable population because of their dependence and inability to communicate their needs. Oral health disparities continue to pose critical challenges, as ECC is the most common chronic disease of childhood.
View Article and Find Full Text PDFThe mediating role of health literacy for COVID-19 between preventive behaviors and quality of life.
Appl Nurs Res
February 2025
School of Gerontology and Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan.. Electronic address:
Background: The coronavirus disease 2019 (COVID-19) pandemic rapidly developed around the world. Plenty of health information about the virus was available from multiple media platforms, but such information was not always accurate. Identifying misinformation depends on an individual's health literacy.
View Article and Find Full Text PDFScreening for immunodominant epitopes of SARS-CoV-2 based on CD8 T cell responses from individuals with HLA-A homozygous alleles.
Mol Immunol
January 2025
Department of Medical Laboratory Center, General Hospital of Central Theater Command, Wuhan, Hubei 430015, PR China. Electronic address:
Purpose: SARS-CoV-2-specific CD8 cytotoxic T lymphocytes (CTLs) are crucial in viral clearance, disease progression, and reinfection control. However, numerous SARS-CoV-2 immunodominant CTL epitopes theoretically are still unidentified due to the genetic polymorphism of human leukocyte antigen class I (HLA-I) molecules.
Methods: The CTL epitopes of SARS-CoV-2 were predicted by the epitope affinity and immunogenicity prediction platforms: the NetMHCpan and the PromPPD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!