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Bifurcating Method for Subcutaneous Indwelling of Nonabsorbable Threads.
Plast Reconstr Surg Glob Open
January 2025
From the Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.
Subcutaneous indwelling of nonabsorbable threads for tissue fixation and tension reduction is often used in plastic surgery and is applied in breast reduction surgery, umbilicoplasty, and in frontalis muscle lifting for congenital ptosis. However, in a few cases, exposure of the indwelling thread necessitates its removal. Exposure of the indwelling threads mostly occurs due to exposure of the knots.
View Article and Find Full Text PDFThe Complex Energy Landscape of miRFP709, a 4-Knotted Protein, Results in Its Irreversible Denaturation.
J Phys Chem B
January 2025
Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India.
Knotted proteins have a unique topological feature with an open knot, and the physiological significance of these knots remains elusive. In addition, these proteins challenge our understanding of the protein folding process, and whether they retain their native state during unfolding/refolding cycles like other proteins is debated. Most folding studies on knotted proteins have been performed on 3 and 5 knots, monitoring the tryptophan fluorescence.
View Article and Find Full Text PDFEmergence of Chirality in an Optically Active Two-Dimensional Crystal with a Spiral Surface Pattern.
J Am Chem Soc
January 2025
RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Some one-dimensional (1D) crystals containing a screw dislocation along their longer axis exhibit a helical twist due to lattice strain. These chiral structures have been thoroughly investigated by using transmission electron microscopy. However, whether two-dimensional (2D) crystals with a spiral surface pattern, presumably containing a screw dislocation, are structurally chiral remains unclear because their internal structures are not visible.
View Article and Find Full Text PDFDual-Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution?
FEBS J
January 2025
Department of Biological Sciences, Chungnam National University, Daejeon, Korea.
Previous studies have identified three families of knotted phytochrome photoreceptors in cyanobacteria. We describe a fourth type: 'hybrid' phytochromes with putative bilin-binding cysteine residues in both their N-terminal 'knot' extensions and cGMP-phosphodiesterase/adenylate cyclase/FhlA (GAF) domains, which we designate as dual-cysteine bacteriophytochromes (DCBs). Recombinant expression of DCBs in Escherichia coli yields photoactive phycocyanobilin (PCB) adducts with red/far-red photocycles similar to those of the GAF-Cys-containing cyanobacterial phytochromes (Cph1s).
View Article and Find Full Text PDFPhase transitions, Dirac and Weyl semimetal states in MnGeBiTe.
Sci Rep
January 2025
Saint Petersburg State University, St. Petersburg, 198504, Russia.
Using angle-resolved photoemission spectroscopy (ARPES) and density functional theory (DFT), an experimental and theoretical study of changes in the electronic structure (dispersion dependencies) and corresponding modification of the energy band gap at the Dirac point (DP) for topological insulator (TI) [Formula: see text] have been carried out with gradual replacement of magnetic Mn atoms by non-magnetic Ge atoms when concentration of the latter was varied from 10% to 75%. It was shown that when Ge concentration increases, the bulk band gap decreases and reaches zero plateau in the concentration range of 45-60% while trivial surface states (TrSS) are present and exhibit an energy splitting of 100 and 70 meV in different types of measurements. It was also shown that TSS disappear from the measured band dispersions at a Ge concentration of about 40%.
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