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Age-specific vulnerability and high prevalence of delirium in pediatric intensive care based on a prospective cohort study.
Sci Rep
December 2024
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Delirium, a neuropsychiatric syndrome characterized by acute disruptions in attention and awareness, significantly impacts children in Pediatric Intensive Care Units (PICUs), leading to prolonged hospitalization, increased infection risk, and dependence on mechanical ventilation. Despite growing recognition, its true burden and risk factors in children remain poorly understood. This prospective cohort study investigated the prevalence, characteristics, and potential therapeutic targets for delirium in 890 children admitted to a tertiary PICU between January and December 2022.
View Article and Find Full Text PDFCharacteristics and outcomes of patients with Guillain-Barré syndrome who were admitted to the intensive care unit: a retrospective observational study.
J Int Med Res
December 2024
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
Objective: To evaluate characteristics and outcomes in critically ill patients with Guillain-Barré syndrome (GBS).
Methods: Consecutive adults with GBS who required intensive care unit (ICU) admission at a tertiary-care hospital between 1999 and 2020 were enrolled into this retrospective cohort study. Demographics, clinical data and patient outcomes were compared between patients who did or did not receive mechanical ventilation (MV).
Surgical Complications Following Appendectomy in Obese Patients: A Single Tertiary Care Center Study.
Cureus
November 2024
General Surgery, King Abdulaziz Medical City, Riyadh, SAU.
Background The escalating global prevalence of obesity raises concerns about its implications for health outcomes. While obesity is acknowledged as a major risk factor for various diseases, its impact on appendicitis and appendectomy outcomes remains less explored. Methods Data on overweight and obese adults aged 18 to 65 treated for appendicitis in King Abdulaziz Medical City in Riyadh, Saudi Arabia were collected retrospectively.
View Article and Find Full Text PDFTreatment Patterns and Healthcare Costs Among Patients with Stroke and Spasticity: A 2-Year Longitudinal Study.
Neurol Ther
December 2024
Ipsen, 1 Main Street, Suite 700, Cambridge, MA, 02142, USA.
Introduction: Post-stroke spasticity (PSS) occurs in ~25-43% of patients between 2 weeks and 3 months following a stroke. This retrospective claims study examined the occurrence of spasticity, treatment patterns, healthcare resource utilization, and healthcare costs among patients who experienced a stroke over a 2-year period.
Methods: Analyses were conducted using healthcare claims from the IQVIA PharMetrics Plus database of commercially/self-insured members from 2015 to 2021.
Timing of Dexamethasone Initiation and Its Impact on the Outcome of COVID-19 Patients.
Cureus
November 2024
Division of Internal Medicine, Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNGHA), Riyadh, SAU.
Introduction COVID-19 emerged in Wuhan in December 2019 and was declared a pandemic in March 2020. Severe cases manifest with respiratory distress. Corticosteroids, initially debated, are now recommended for severe cases following the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial findings.
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