We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine homozygous persons and in bovine spongiform encephalopathy. These results indicate no adaptation of the agent in a different genetic background.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258451 | PMC |
| http://dx.doi.org/10.3201/eid2606.191116 | DOI Listing |
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