Background: Tracheotomy, through its ability to wean patients off ventilation, can shorten ICU length of stay and in doing so increase ICU bed capacity, crucial for saving lives during the COVID-19 pandemic. To date, there is a paucity of patient selection criteria and prognosticators to facilitate decision making and enhance precious ICU capacity.
Methods: Prospective study of COVID-19 patients undergoing tracheotomy (n = 12) over a 4-week period (March-April 2020). Association between preoperative and postoperative ventilation requirements and outcomes (ICU stay, time to decannulation, and death) were examined.
Results: Patients who sustained FiO ≤ 50% and PEEP ≤ 8 cm H O in the 24 hours pretracheotomy exhibited a favorable outcome. Those whose requirements remained below these thresholds post-tracheotomy could be safely stepped down after 48 hours.
Conclusion: Sustained FiO ≤ 50% and PEEP ≤ 8 cm H O in the 48 hours post-tracheotomy are strong predictive factors for a good outcome, raising the potential for these patients to be stepped down early, thus increasing ICU capacity.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280616 | PMC |
http://dx.doi.org/10.1002/hed.26280 | DOI Listing |
Cureus
December 2024
College of Medicine, Qassim University, Buraydah, SAU.
Background Coronavirus disease (COVID-19), a widespread viral illness, has been linked to a range of respiratory and other systemic symptoms. Along with the respiratory symptoms caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), many extrapulmonary manifestations have also been reported. This study was conducted to report the ocular manifestations of COVID-19 in confirmed cases from the Qassim region, of Saudi Arabia.
View Article and Find Full Text PDFJ Tradit Complement Med
January 2025
National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei City, 112026, Taiwan.
Amidst growing concerns over COVID-19 aftereffects like fatigue and cognitive issues, NRICM101, a traditional Chinese medicine, has shown promise. Used by over 2 million people globally, it notably reduces hospitalizations and intubations in COVID-19 patients. To explore whether NRICM101 could combat COVID-19 brain fog, we tested NRICM101 on hACE2 transgenic mice administered the S1 protein of SARS-CoV-2, aiming to mitigate S1-induced cognitive issues by measuring animal behaviors, immunohistochemistry (IHC) staining, and next-generation sequencing (NGS) analysis.
View Article and Find Full Text PDFCan Med Educ J
December 2024
Department of Medicine, Cleveland Clinic, Ohio, USA.
Background: The COVID-19 pandemic disrupted the healthcare system, affecting physician wellbeing. The consequences of reduced time spent with patients at bedside during the pandemic has not been investigated. The objectives of this study include assessing time spent with patients, physician wellbeing and patient satisfaction before and during the pandemic.
View Article and Find Full Text PDFBMJ Open
December 2024
Perinatal HIV Research Unit (PHRU), University of the Witwatersrand Johannesburg, Johannesburg, Gauteng, South Africa.
Purpose: In the setting of an established childhood pneumococcal vaccination programme with immediate initiation and treatment of antiretroviral therapy (ART) for people living with HIV (PLWH), the risk of adult pneumococcal community-acquired pneumonia (CAP) is not recently described. We aimed to investigate CAP incidence, recurrence, mortality, risk factors and microbiology before and during the COVID-19 pandemic.
Participants: Adults aged ≥18 years were enrolled in three South African provinces from March 2019 to October 2021, with a brief halt during the initial COVID-19 lockdown.
BMJ Open
December 2024
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Québec, Canada
Objectives: To describe the impact of the COVID-19 pandemic on hypertension diagnosis and management in UK primary care.
Design: Population-based cohort study.
Setting: Over 2000 general practices across the UK contributing to the Clinical Practice Research Datalink.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!