Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233606 | PMC |
| http://dx.doi.org/10.1093/cz/zoz033 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chemosensory Cues Modulate Women's Jealousy Responses to Vocal Femininity.
Arch Sex Behav
January 2025
Department of Applied Social Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Jealousy responses to potential mating rivals are stronger when those rivals display cues indicating higher mate quality. One such cue is vocal femininity in women's voices, with higher-pitched voices eliciting greater jealousy responses. However, cues to mate quality are not evaluated in isolation.
View Article and Find Full Text PDFOncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors.
EMBO Mol Med
January 2025
Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.
Oncolytic viruses (OV) expressing bispecific T-cell engagers (BiTEs) are promising tools for tumor immunotherapy but the range of target tumors is limited. To facilitate effective T-cell stimulation with broad-range applicability, we established membrane-associated T-cell engagers (MATEs) harboring the protein transduction domain of the HIV-Tat protein to achieve non-selective binding to target cells. In vitro, MATEs effectively activated murine T cells and improved killing of MC38 colon carcinoma cells.
View Article and Find Full Text PDFComparison of Patient Comfort and Acceleration Exposure During Lifting and Loading Operations Using Manual and Powered Stretchers.
Prehosp Emerg Care
January 2025
Graduate School of Health and Welfare, Niigata University of Health and Welfare, Niigata, Japan.
Objectives: To compare the effects of powered and manual stretchers on participants' perceived comfort and measured acceleration during lifting and loading operations.
Methods: This non-randomized, laboratory-based crossover study involved forty-one participants (thirty-one firefighters and ten third-year paramedic students) who served as simulated patients experiencing lifting, lowering, loading, and unloading maneuvers using manual and powered stretchers. Four stretcher types were evaluated: one powered stretcher (Power-PRO XT) and three manual stretchers (Matsunaga GT, Exchange 4070, Scad Mate), with each group using the manual stretcher they routinely operated.
Times needed to evolve mating cues under allopatry and parapatry.
J Evol Biol
December 2024
Department of Mathematics and Statistics, University of Reading, UK.
The time needed for the evolution of mating cues that distinguish species, such as species-specific songs or plumage coloration in birds, has received little attention. Aiming to gain some understanding of the timing of the evolutionary process we here present models of how mating cues evolve in populations split into subpopulations between which there may (parapatry) or may not (allopatry) be migration. Mating cues can be either neutral or directly selected.
View Article and Find Full Text PDFApplication of Microsponge Drug Platform to Enhance Methotrexate Administration in Rheumatoid Arthritis Therapy.
Pharmaceutics
December 2024
Nanofaber S.r.l., Via Anguillarese 301, 00123 Rome, Italy.
Background/objectives: This study aimed to develop a novel nanotechnological slow-release drug delivery platform based on hyaluronic acid Microsponge (MSP) for the subcutaneous administration of methotrexate (MTX) in the treatment of rheumatoid arthritis (RA). RA is a chronic autoimmune disease characterized by joint inflammation and damage, while MTX is a common disease-modifying antirheumatic drug (DMARD), the conventional use of which is limited by adverse effects and the lack of release control.
Methods: MSP were synthesized as freeze-dried powder to increase their stability and allow for a facile reconstitution prior to administration and precise MTX dosing.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!