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The impact of restricted length of treatment field and anthropometric factors on selection of head and neck cancer patients for treatment on the MR-Linac. | LitMetric

AI Article Synopsis

  • This study examines how a limited craniocaudal (CC) field length of less than 20 cm affects head and neck cancer patients' eligibility for treatment with a specific MR-Linac technique.
  • It analyzes data from 110 patients who received radical radiotherapy, focusing on how factors like gender, height, neck length, and neck position impact CC field length.
  • Results show that 95% of patients had a CC length under 20 cm, with significant differences based on gender and neck position, indicating that a hyo-sternal neck length less than 14.6 cm can determine suitability for the MR-Linac treatment.

Article Abstract

Objective: This study investigates the impact of a restricted craniocaudal (CC) field length of <20 cm on the selection of head and neck cancer (HNC) patients who can be treated on the MR-Linac using a single isocentre technique. We also assess the effects of anthropometric factors and the neck position on the CC field length.

Methods: 110 HNC patients who underwent radical primary or adjuvant radiotherapy were retrospectively analysed. We assessed the proportion of treatment fields with a CC length of <20 cm and the effects of gender, height, hyo-sternal neck length (distance from superior surface of hyoid to sternal notch measured on the coronal reconstruction of the planning CT) and neck position on CC length.

Results: 95% of HNC patients had a CC field length <20 cm. Female patients showed a significantly shorter median CC length than male patients in both extended ( = 0.0003) and neutral ( = 0.008) neck positions. Neck position influenced the median CC length with neutral neck being significantly shorter than extended neck ( = 0.0119). Patient height and hyo-sternal neck length showed positive correlation with the CC length, with neck length in neutral position having the strongest correlation ( = 0.65, = 0.0001 and = 0.63, < 0.0001, respectively for extended neck; = 0.55, = 0.0070 and = 0.80, < 0.0001, respectively for neutral neck). A hyo-sternal neck length of <14.6 cm predicted a CC length of <20 cm in neutral neck position.

Conclusion: The majority of patients with HNC at the Royal Marsden Hospital have anthropometric features compatible with their being treated on the MR-Linac using a single isocentre technique. The absolute CC field size may vary according to primary tumour site, patient factors and neck position. A hyo-sternal neck length cut-off of 14.6 cm in the neutral neck position can be used as a surrogate marker for suitability of treatment on MR-Linac.

Advances In Knowledge: This paper highlights the potential impact of a restricted CC field in HNC patient selection for the MR-Linac treatment. This is the first report to suggest the use of neck length as a surrogate marker for suitability of treatment on the MR-Linac.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336067PMC
http://dx.doi.org/10.1259/bjr.20200023DOI Listing

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