An accurate, safe, environmentally friendly, fast and sensitive electrochemical biosensors were developed to detect xanthine in serum. The metal-organic framework ZIF-8 was synthesised and elemental gold was supported on the surface of ZIF-8 by reduction method to synthesise Ag-ZIF-8. The mesoporous carbon material and the synthesised Ag-ZIF-8 were, respectively, applied to a glassy carbon electrode to construct biosensors. The constructed biosensor has a good linear relation in the range of 1-280 μmol l of xanthine and the detection limit is 0.167 μmol l. The relative standard deviation value in serum samples was <5%, and the recoveries were 96-106%, indicating the good selectivity, stability and reproducibility of this electrochemical biosensor.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8676153 | PMC |
| http://dx.doi.org/10.1049/iet-nbt.2018.5342 | DOI Listing |
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