To implement and assess pharmacy students' opinions of a new student organization that uses visual, linguistic, and performing arts to bring emotional support, joy, and healing to patients. Pro Mé, an on-campus, community-service organization was formed at the Appalachian College of Pharmacy for students with talent or background in the arts. Members organized performances and art events at local assisted living facilities, long-term care facilities, hospitals, mobile medical clinics, schools, etc. The group also promoted various public health care initiatives. A survey was conducted to assess the impact of participation in the organization on members. Pro Mé began in March 2018 with 27 initial members. Approximately one year later, the organization had grown to 66 members and become the largest student organization on campus. During its first year, members participated in a wide array of community service events. On the survey, students reported having increased empathy and that participation in Pro Mé had enhanced their overall pharmacy school experience. Establishing a performing arts organization like Pro Mé at other pharmacy schools could provide students with a creative outlet, leadership opportunities, and patient contact experiences that can increase their compassion and empathy and thereby better prepare them to be practicing clinicians.
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http://dx.doi.org/10.5688/ajpe7723 | DOI Listing |
Molecules
December 2024
Department of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.
Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis and potential hepatotoxicity. This study investigates the cytotoxic (MTT assay) and pro-apoptotic effects of metamizole and its primary metabolites, 4-methylaminoantipyrine (4-MAA) and 4-aminoantipyrine (4-AA), on the LX-2 liver cell line. These metabolites are implicated in both the therapeutic and adverse effects of the drug.
View Article and Find Full Text PDFACS Macro Lett
September 2024
POLYMAT University of the Basque Country UPV/EHU, Joxe Mari Korta Center. Avda. Tolosa 72, 20018, Donostia-San Sebastián, Spain.
Multiresponsive hydrogels are valuable as biomaterials due to their ability to respond to multiple biologically relevant stimuli, i.e., temperature, pH, or reactive oxygen species (ROS), which can be present simultaneously in the body.
View Article and Find Full Text PDFPharmaceutics
July 2024
Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Acne vulgaris, a prevalent skin condition, arises from an imbalance in skin flora, fostering bacterial overgrowth. Addressing this issue, clindamycin molecularly imprinted polymeric nanoparticles (Clin-MIP) loaded onto polyurethane nanofiber scaffolds were developed for acne treatment. Clin-MIP was synthesized via precipitation polymerization using methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA), and azoisobutyronitrile (AIBN) as functional monomers, crosslinkers, and free-radical initiators, respectively.
View Article and Find Full Text PDFRespir Res
April 2024
Division of Allergy & Immunology, University of Nebraska Medical Center, Omaha, NE, USA.
Background: Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) induce recruited, transitioning murine lung monocytes/macrophages, yet their cellular role remains unclear.
Methods: CCR2 RFP mice were intratracheally instilled with high concentration ODE (25%), LPS (10 μg), or gram-positive peptidoglycan (PGN, 100 μg) for monocyte/macrophage cell-trafficking studies.
Cancers (Basel)
February 2024
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Venetoclax, a highly selective, oral B-cell lymphoma 2 inhibitor, provides a robust targeted-therapy option for the treatment of chronic lymphocytic leukemia (CLL), including patients with high-risk del(17p)/mutated- and immunoglobulin heavy variable region unmutated CLL and those refractory to chemoimmunotherapy across all age groups. Due to the potent pro-apoptotic effect of venetoclax, treatment initiation carries a risk of tumor lysis syndrome (TLS). Prompt and appropriate management is needed to limit clinical TLS, which may entail serious adverse events and death.
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