AI Article Synopsis
- The study aimed to find the most cost-effective way to prevent multidrug-resistant organisms (MDROs) in ICUs, focusing on areas with limited health resources.
- The research included 12 ICUs across four hospitals, analyzing costs and infection rates for different prevention strategies over a year with 2046 subjects.
- Hand hygiene emerged as the most effective and least costly method, while single-room isolation was the most expensive and least effective, suggesting that hand hygiene is the best strategy for infection control in ICUs in developing countries.
Article Abstract
The aim of this study was to determine the most cost-effective strategy for the prevention and control of multidrug-resistant organisms (MDROs) in intensive care units (ICUs) in areas with limited health resources. The study was conducted in 12 ICUs of four hospitals. The total cost for the prevention of MDROs and the secondary attack rate (SAR) of MDROs for each strategy were collected retrospectively from 2046 subjects from January to December 2017. The average cost-effectiveness ratio (CER), incremental cost-effectiveness ratio (ICER) and cost-effectiveness acceptability curve were calculated. Hand hygiene (HH) had the lowest total cost (2149.6 RMB) and SAR of MDROs (8.8%) while single-room isolation showed the highest cost (33 700.2 RMB) and contact isolation had the highest SAR of MDROs (31.8%). The average cost per unit infection prevention was 24 427.8 RMB, with the HH strategy followed by the environment disinfection strategy (CER = 21 314.67). HH had the highest iterative cost effect under willingness to pay less than 2000 RMB. Due to the low cost for repeatability and obvious effectiveness, we conclude that HH is the optimal strategy for MDROs infections in ICUs in developing countries. The cost-effectiveness of the four prevention strategies provides some reference for developing countries but multiple strategies remain to be examined.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439291 | PMC |
| http://dx.doi.org/10.1017/S0950268820001120 | DOI Listing |
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Article Synopsis
- The study aimed to find the most cost-effective way to prevent multidrug-resistant organisms (MDROs) in ICUs, focusing on areas with limited health resources.
- The research included 12 ICUs across four hospitals, analyzing costs and infection rates for different prevention strategies over a year with 2046 subjects.
- Hand hygiene emerged as the most effective and least costly method, while single-room isolation was the most expensive and least effective, suggesting that hand hygiene is the best strategy for infection control in ICUs in developing countries.
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