Ruthenacarborane-Phenanthroline Derivatives as Potential Metallodrugs.

Molecules

Institute of Inorganic Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Published: May 2020

AI Article Synopsis

  • Ruthenium-based complexes are being explored as potential metallodrugs, leading to the synthesis of four specific Ru complexes with different ligands.
  • The synthesized complexes were characterized through various methods, including single crystal diffraction analysis, revealing detailed structural information.
  • These complexes demonstrate stability in air and moisture, exhibit good solubility in organic solvents, but have low solubility in water.

Article Abstract

Ruthenium-based complexes have received much interest as potential metallodrugs. In this work, four Ru complexes bearing a dicarbollide moiety, a carbonyl ligand, and a phenanthroline-based ligand were synthesized and characterized, including single crystal diffraction analysis of compounds , , and and an observed side product . Complexes - are air and moisture stable under ambient conditions. They show excellent solubility in organic solvents, but low solubility in water.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287719PMC
http://dx.doi.org/10.3390/molecules25102322DOI Listing

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