A mild catalytic modification of dihydropyrrolo[2,1-a]isoquinolines with various phenols via the formation of heteroarene cation radicals as key intermediates has been developed. A range of direct cross-coupling products could be obtained in acceptable to excellent yields (up to 98%) in the presence of FeCl2.
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http://dx.doi.org/10.1039/d0ob00917b | DOI Listing |
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