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Observation of Laser-Assisted Dynamic Interference by Attosecond Controlled Photoelectron Spectroscopy.
Phys Rev Lett
December 2024
Institute of Atomic and Molecular Physics, Jilin University, Changchun 130012, China.
We have observed the laser-assisted dynamic interference in the electron spectra triggered by attosecond pulse trains. The fingerprints of finer interference fringes, much smaller than the laser photon energy, have been clearly identified experimentally. Our measurements are successfully reproduced by theoretical simulations utilizing the numerical solution to the time-dependent Schrödinger equation and the strong-field approximation.
View Article and Find Full Text PDFUpdated Geriatrics Competencies for Graduating Medical Students: Training Physicians to Provide Age-Friendly Care.
Acad Med
December 2024
R.M. Leipzig is professor and vice chair emerita, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Purpose: Medical student education in geriatrics is a critical need for every doctor-in-training as the population ages, with fewer than 7,000 geriatricians, and older patients, who now approach 20% of the U.S. population, having unique health care needs.
View Article and Find Full Text PDFThermostability Enhancement of Tagatose 4-Epimerase through Protein Engineering and Whole-Cell Immobilization.
J Agric Food Chem
January 2025
School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education, Jiangnan University, Wuxi 214122, China.
d-Tagatose, a rare sugar endowed with a low-calorie property, superior taste quality, and probiotic functionality, has garnered significant research attention. However, the prevailing biological production methods relying on β-galactosidase and l-arabinose isomerase face challenges including high cost and suboptimal conversion efficiency. Consequently, it is of great research significance to find efficient alternative routes for d-tagatose synthesis.
View Article and Find Full Text PDFSuppression of thrombospondin-1-mediated inflammaging prolongs hematopoietic health span.
Sci Immunol
January 2025
Division of Hematology and Oncology, Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
Chronic low-grade inflammation observed in older adults, termed inflammaging, is a common feature underlying a multitude of aging-associated maladies including a decline in hematopoietic activity. However, whether suppression of inflammaging can preserve hematopoietic health span remains unclear, in part because of a lack of tools to measure inflammaging within hematopoietic stem cells (HSCs). Here, we identify thrombospondin-1 (Thbs1) as an essential regulator of inflammaging within HSCs.
View Article and Find Full Text PDFSNIPR alert! Making T cells more precise killers.
Sci Immunol
January 2025
Department of Immunology and Microbiology, Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL 33458, USA.
A cell engineering approach demonstrates that precise regulation of cell signaling can be achieved using both endogenous and synthetic ligands.
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