Background: Malaria remains a public health problem in developing countries and Malawi is no different. Although there has been an improvement in reducing malaria in Malawi, it remains a problem, especially in children less than five years old. The primary objective of the study was to assess whether socio-economic, geographic and demographic factors are associated with malaria, using the generalized additive mixed model (GAMM).
Data And Methodology: The study used a 2017 dataset from the Malawi Malaria Indicator Survey (MMI) with a total number of 2724 children under five years old. The study also utilized the GAMM to analyze data. The outcome was that either the child had malaria or did not, as detected using the malaria Rapid Diagnostic Test (RDT) (Ayele et al., 2014a).
Results: In this study, more than 37 % of the total number of children who were tested showed a positive malaria result. In addition, the results from this study using GAMM indicated that anaemia, mother's education level, wealth index, child's age, the altitude of the place of residence, region, place of residence, toilet facility and electricity were significantly associated with a positive malaria RDT.
Conclusion: The study revealed that socio-economic, geographical and demographic variables are the key factors in improving malaria vectors in children. Improving income levels and supporting the poorer rural community mostly from the Central Region would be a great achievement in reducing malaria vectors in Malawi. In addition, improving health care in rural areas, especially at higher altitudes, would contribute to controlling malaria and reducing anaemia.
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http://dx.doi.org/10.1016/j.heliyon.2020.e03946 | DOI Listing |
PLoS One
January 2025
Instituto René Rachou, Fiocruz Minas, Fundação Oswaldo Cruz (Fiocruz), Belo Horizonte, Minas Gerais, Brazil.
Background: To develop an effective vaccine against Plasmodium vivax, the most widely dispersed human malaria parasite, it is critical to understand how coinfections with other pathogens could impact malaria-specific immune response. A recent conceptual study proposed that Epstein-Barr virus (EBV), a highly prevalent human herpesvirus that establishes lifelong persistent infection, may influence P. vivax antibody responses.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda, Bambili, North West Region, Cameroon.
Background: Malaria and HIV are leading causes of death in Africa, including Cameroon. Antiretroviral therapy (ART) is expected to boost immunity and reduce vulnerability to opportunistic infections. Reports on comorbidities including malaria are common in Cameroon.
View Article and Find Full Text PDFmSphere
January 2025
Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Malaria is a highly lethal infectious disease caused by parasites. These parasites are transmitted to vertebrate hosts when mosquitoes of the genus probe for a blood meal. Sporozoites, the infectious stage of , transit to the liver within hours of injection into the dermis.
View Article and Find Full Text PDFCancer Commun (Lond)
January 2025
Mortality, Health and Epidemiology Department, Institute for Demographic Studies (Ined), Aubervilliers, France.
Mikrobiyol Bul
January 2025
Sağlık Bilimleri Üniversitesi, Kayseri Şehir Eğitim ve Araştırma Hastanesi, Parazitoloji Laboratuvarı, Kayseri.
Sıtma, her yıl dünya nüfusunun yarısından fazlası için ciddi bir tehdit oluşturmaya devam etmektedir. Hastalığa neden olan Plasmodium parazitleri, yalnızca insanlarla sınırlı kalmayıp sürüngenlerden kuşlara, memelilerden diğer omurgalılara dek geniş enfeksiyon yelpazesine sahiptir. Plasmodium türleri, çevredeki değişikliklere uyum sağlamalarını sağlayan olağanüstü genetik esnekliğe sahiptir ve bu da onlara sıtma ilaçları gibi tedavi edici maddelere karşı hızla direnç geliştirme ve konakçı özgüllüğünü değiştirme potansiyeli verir.
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