Background: Congenital syphilis is still a problem for developing countries, despite the screening options and low cost treatment.
Clinical Case: 23-day-old male patient with copper colored macules and scaling in palms and soles, as well as hepatomegaly. It was reported a negative TORCH test with VDRL of 1:512 and positive FTA ABS. As maternal history, patient had a 21 year old mother with negative VDRL at 12 weeks pregnant. Despite maternal history, with positive VDRL and FTA ABS, besides the clinical triad, it was diagnosed congenital syphilis.
Conclusion: Factors that most influence failing in the prevention of congenital syphilis are inadequate prenatal care, misinterpreting diagnostic tests and not establishing monitoring programs. It is necessary to carry out VDRL tests twice during pregnancy to women who have a risk factor.
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