AI Article Synopsis
- Osteomyelitis is an infection of the bone primarily caused by methicillin-resistant Staphylococcus (MRS), with vancomycin being the preferred treatment option.
- This case report highlights a successful treatment using a combination of daptomycin and ceftaroline for a 54-year-old woman with osteomyelitis due to methicillin-resistant Staphylococcus epidermidis (MRSE).
- The report also emphasizes the important role of clinical pharmacists in managing antimicrobial treatments and stewardship programs.
Article Abstract
Osteomyelitis is an infection involving bone. is the pathogen most frequently implicated; less frequently involved are other gram-positive organisms, such as and also gram-negative organisms. The antibiotic of choice for treatment of osteomyelitis caused by methicillin-resistant staphylococci (MRS) is vancomycin, although other alternatives such as daptomycin or teicoplanin are also considered. Osteomyelitis caused by MRS can be difficult to treat safely and effectively. This case report describes the successful use of daptomycin combined with ceftaroline for the treatment of osteomyelitis caused by methicillin-resistant (MRSE) in a 54-year-old woman, emphasising the clinical pharmacist's role in antimicrobial stewardship programmes. This alternative combination has been studied in the treatment of methicillin-resistant (MRSA), but it may also be useful in MRSE.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403780 | PMC |
| http://dx.doi.org/10.1136/ejhpharm-2019-002183 | DOI Listing |
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