Deep networks can learn complex problems, however, they suffer from overfitting. To solve this problem, regularization methods have been proposed that are not adaptable to the dynamic changes in the training process. With a different approach, this paper presents a regularization method based on the Singular Value Decomposition (SVD) that adjusts the learning model adaptively. To this end, the overfitting can be evaluated by condition numbers of the synaptic matrices. When the overfitting is high, the matrices are substituted with their SVD approximations. Some theoretical results are derived to show the performance of this regularization method. It is proved that SVD approximation cannot solve overfitting after several iterations. Thus, a new Tikhonov term is added to the loss function to converge the synaptic weights to the SVD approximation of the best-found results. Following this approach, an Adaptive SVD Regularization (ASR) is proposed to adjust the learning model with respect to the dynamic training characteristics. ASR results are visualized to show how ASR overcomes overfitting. The different configurations of Convolutional Neural Networks (CNN) are implemented with different augmentation schemes to compare ASR with state-of-the-art regularization methods. The results show that on MNIST, F-MNIST, SVHN, CIFAR-10 and CIFAR-100, the accuracies of ASR are 99.4%, 95.7%, 97.1%, 93.2% and 55.6%, respectively. Although ASR improves the overfitting and validation loss, its elapsed time is not significantly greater than the learning without regularization.
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http://dx.doi.org/10.1016/j.neunet.2020.04.021 | DOI Listing |
Int J Pharm
January 2025
Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Hydrophobicity is associated with drug transport across membranes and is expressed as the partition coefficient log P for neutral drugs and the distribution coefficient log D for acidic and basic drugs. The log P and log D predictions are deductively (or with artificial intelligence) estimated as the sum of the partial contributions of the scaffold and substituents of a single molecule and are used widely and affirmatively. However, their predictions have not always been comprehensively accurate beyond scaffold differences.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2024
Lab. of Biomedical Diagnostics, Eindhoven University of Technology, Eindhoven, The Netherlands.
Background And Objective: The integration of ultrafast Doppler imaging with singular value decomposition clutter filtering has demonstrated notable enhancements in flow measurement and Doppler sensitivity, surpassing conventional Doppler techniques. However, in the context of transthoracic coronary flow imaging, additional challenges arise due to factors such as the utilization of unfocused diverging waves, constraints in spatial and temporal resolution for achieving deep penetration, and rapid tissue motion. These challenges pose difficulties for ultrafast Doppler imaging and singular value decomposition in determining optimal tissue-blood (TB) and blood-noise (BN) thresholds, thereby limiting their ability to deliver high-contrast Doppler images.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
November 2024
Over the past decade, ultrasound microvasculature imaging has seen the rise of highly sensitive techniques, such as ultrafast power Doppler (UPD) and ultrasound localization microscopy (ULM). The cornerstone of these techniques is the acquisition of a large number of frames based on unfocused wave transmission, enabling the use of singular value decomposition (SVD) as a powerful clutter filter to separate microvessels from surrounding tissue. Unfortunately, SVD is computationally expensive, hampering its use in real-time UPD imaging and weighing down the ULM processing chain, with evident impact in a clinical context.
View Article and Find Full Text PDFSci Rep
October 2024
College of Computer and Information Science, Chongqing Normal University, Chongqing, 401331, China.
Digital images have become an important way of transmitting information, and the risk of attacks during transmission is increasing. Image watermarking is an important technical means of protecting image information security and plays an important role in the field of information security. In the field of image watermarking technology, achieving a balance between imperceptibility, robustness, and embedding capacity is a key issue.
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