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Central arterial stiffness in young adults with perinatal HIV exposure & infection.
AIDS
January 2025
Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, Buffalo NY.
Objective: To compare arterial stiffness between young adults with perinatally acquired HIV (YAPHIV) and young adults perinatally HIV exposed but uninfected (YAPHEU).
Design: Cross-sectional analysis of pulse wave velocity (PWV) measures among participants with echocardiography in the PHACS Cardiac Toxicity Substudy.
Methods: A total of 150 participants (95 YAPHIV, 55 YAPHEU, mean 23.
Combining Hyperpolarized Xe MR Imaging and Spectroscopy to Non-Invasively Estimate Pulmonary Vascular Resistance.
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Medical Physics Graduate Program, Duke University, Durham, North Carolina, United States.
Hyperpolarized Xe MRI/MRS enables quantitative mapping of function in lung airspaces, membrane tissue, and red blood cells (RBCs) within the pulmonary capillaries. The RBC signal also exhibits cardiogenic oscillations that are reduced in pre-capillary pulmonary hypertension (PH). This effect is obscured in patients with concomitant defects in transfer from airspaces to RBCs, which increase RBC oscillation amplitudes.
View Article and Find Full Text PDFEvidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis.
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Neuromotor Behavior and Exercise, University of Münster, Münster, Germany.
Background And Objectives: This is a protocol for a living systematic review and meta-analysis.This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.
View Article and Find Full Text PDFInvestigating cognitive-physical task interaction during self-paced cycling: a Granger Causality study.
Psychol Sport Exerc
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Mind Brain and Behavior Research Center, CIMCYC-UGR, University of Granada, Spain; Department of Experimental Psychology, University of Granada, Spain.
Self-pacing physical exercise is thought to rely on high-order cognitive processing (e.g., attentional control to monitor afferent cardiovascular feedback for exercise goals).
View Article and Find Full Text PDFModeling the effects of thin filament near-neighbor cooperative interactions in mammalian myocardium.
J Gen Physiol
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Department of Animal, Veterinary, and Food Sciences, College of Agricultural and Life Sciences, University of Idaho, Moscow, ID, USA.
The mechanisms underlying cooperative activation and inactivation of myocardial force extend from local, near-neighbor interactions involving troponin-tropomyosin regulatory units (RU) and crossbridges (XB) to more global interactions across the sarcomere. To better understand these mechanisms in the hearts of small and large mammals, we undertook a simplified mathematical approach to assess the contribution of three types of near-neighbor cooperative interactions, i.e.
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