Herein, we report a rare case of a stress fracture through a pre-existing non-ossifying fibroma (NOF) of the femur of a 12-year-old child that raised suspicion of a malignancy. Although NOFs are very frequent, in the vast majority of cases, they are completely asymptomatic. When encountered in a painful area, especially if combined with atypical radiographic features, they may mimic a malignancy. We discuss the radiographic findings, the differential diagnosis, and the relevant points of the patient's history that helped to establish the diagnosis.
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http://dx.doi.org/10.7759/cureus.7652 | DOI Listing |
Cureus
December 2024
Orthopedics and Traumatology, Ondokuz Mayis University, Samsun, TUR.
Jaffe-Campanacci syndrome (JCS) is a rare disorder characterized by multiple non-ossifying fibromas (NOFs), café-au-lait spots, and other features such as mental retardation and cryptorchidism. It is often clinically and genetically similar to neurofibromatosis type 1 (NF1), complicating diagnosis. This report presents a 17-year-old male with right knee pain, café-au-lait spots, and axillary freckling.
View Article and Find Full Text PDFAm J Sports Med
January 2025
University of Alabama at Birmingham, Birmingham, Alabama, USA.
Background: Benign bone lesions are a common incidental finding in athletes during workup for musculoskeletal complaints, and athletes are frequently advised to halt participation in contact sports. There are no current guidelines to assist clinicians in referring patients with these lesions to a subspecialist or in advising athletes on the safety of returning to sport.
Purpose: To assist sports medicine physicians in appropriate referral for patients with benign bone lesions through presentation of a literature review and the case of an adolescent athlete with a benign bone lesion in a location with a significant fracture risk.
Cureus
November 2024
Orthopedic Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, IND.
Non-ossifying fibroma (NOF) is a benign expansive lytic lesion more frequently found in children and adolescents at the metaphysis of long bones in and around the knee joint, typically resolving spontaneously or by ossification. This report presents a rare case of an 11-year-old child with a pathological subtrochanteric femur fracture attributed to an underlying NOF. We describe the diagnosis and surgical management of curettage and internal fixation using a proximal humerus locking plate, resulting in complete resorption of the lytic zone and an excellent clinical outcome.
View Article and Find Full Text PDFJ Clin Med
September 2024
Department of Physical Medicine and Rehabilitation, Malatya Turgut Ozal University, 44210 Malatya, Turkey.
Fibrous cortical defect (FCD) and non-ossifying fibroma (NOF) are incidentally recognised and benign developmental lesions. The objective of this study was to ascertain the clinical manifestations and symptoms of FCDs/NOFs in children and adolescent patients, to characterise the lesions radiologically using X-ray and MRI techniques, and to determine the relationship between physical activity and the condition. The study included patients under the age of 18 with radiological lesions on their extremities.
View Article and Find Full Text PDFEur Radiol
September 2024
Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Objective: First, to determine the frequency and spectrum of osteoid osteoma (OO)-mimicking lesions among presumed OO referred for radiofrequency ablation (RFA). Second, to compare patient sex and age, lesion location, and rates of primary treatment failure for OO based on histopathology results.
Materials And Methods: A retrospective review was performed of all first-time combined CT-guided biopsy/RFA for presumed OO at a single academic center between January 1990 and August 2023.
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