Background: This study aims to analyze the effect of the body mass index (BMI) on E, P and LH values in females who received intrauterine insemination (IUI) treatment on human chorionic gonadotropin (HCG) day.

Methods: A total of 2319 cycles of IUI-assisted pregnancy treatment were selected in our hospital. Based on the BMI, female infertility patients are divided into three groups: normal weight group, overweight and obese group.

Results: For patients with natural cycles and ≤ 35 years old, there were 440, 178 and 197 cases in the three groups, respectively. For patients with natural cycles and > 35 years old, there were 90, 83 and 81 cycles in the three groups, respectively. For patients with induced ovulation cycle and ≤ 35 years old, there were 425, 203 and 516 cases in the three groups, respectively. For patients with induced ovulation cycle and > 35 years old, there were 26, 26 and 54 cases in the three groups, respectively.

Conclusion: When a patient is ≤35 years old, the BMI affects the E, LH and P values on the day of artificial insemination. However, the BMI is negatively correlated with E, LH and P in IUI on HCG day. After controlling for age and assisted pregnancy, the correlation analysis revealed that the BMI is negatively correlated with hormone E and LH. The higher the BMI was, the lower the levels of hormones E, LH and P became. However, in the present study, the BMI did not significantly improve the clinical pregnancy rate of patients who received IUI.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227362PMC
http://dx.doi.org/10.1186/s12905-020-00963-1DOI Listing

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