Expert Rev Gastroenterol Hepatol
Department of Pathology, Soonchunhyang University Hospital, Seoul, Korea.
Published: July 2020
Introduction: To decrease gastric cancer-related mortality, the Korean National Cancer Screening Program provides biennial screening gastroscopy to all individuals aged >40 years. However, a test-and-treat strategy of for preventing gastric cancer has not been established.
Areas Covered: In this review, we present up-to-date results of endoscopic findings of gastritis, optimal sites for detection, gastric cancer risk assessment using serum pepsinogen, tailored eradication based on the antimicrobial resistance against , and post-eradication surveillance.
Expert Opinion: Here we propose approaches to diagnosis and treatment for preventing gastric cancer, termed 'Screening for in Korea and Eradication (SHAKE)' strategy. This strategy consists of the following: (1) optimized diagnosis, (2) individualized management based on the infection status, and (3) tailored eradication therapy. gastritis can be diagnosed by endoscopic observation of the gastric mucosal pattern at the greater curvature of the corpus. Measurement of the serum pepsinogen I/II ratio is useful for assessing the risk of gastric cancer. As a first-line treatment, tailored eradication based on the results of molecular testing is effective in a country with a high rate of clarithromycin-resistant .
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http://dx.doi.org/10.1080/17474124.2020.1770594 | DOI Listing |
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