A new triterpenoid saponin named Anemonside (1) was isolated from the rhizome of Anemone amurensis (Korsh.) Kom. Its structure was determined by chemical and spectral analysis, including 1D, 2D NMR data, HRESIMS and hydrolysis reaction. The new saponin contains nine sugar units with two O-linked sugar chains, which is relatively rare in natural products. In addition, the cytotoxic activity of Anemonside was evaluated by against A549 and HepG2 cell lines with the MTT method and showed no cytotoxic activity with IC50 over 100 μM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2020.1765344 | DOI Listing |
Publication Analysis
Top Keywords
triterpenoid saponin
8
saponin sugar
8
sugar units
8
korsh kom
8
cytotoxic activity
8
units korsh
4
kom triterpenoid
4
saponin named
4
named anemonside
4
anemonside isolated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!