The PDE7B gene encodes 3'5'-cyclic nucleotide phosphodiesterase (PDE) and a known target in cognitive impairments. Therefore, it is of interest to design and development of potential inhibitors with PDE7B with improved binding features. We document that the amino acid residues such as H186, K190, and G113 of PDE7B protein showed crucial interactions with aspirin for further consideration in this context.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196167 | PMC |
| http://dx.doi.org/10.6026/97320630016183 | DOI Listing |
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