This work experimentally introduces a new single-crystal Nd:YAG end-pumped zigzag slab (EPZS) gain module based on a thin polytetrafluoroethylene (PTFE) sheet as a total internal reflection (TIR) protection layer. In this gain module, a specific optical pump-beam delivery (OPBD) system is used to improve the output beam quality (BQ) of the slab amplifier from 9.4 in a typical OPBD system to 4.7 with the total pump power of 2400 W. The average logarithmic small-signal gain (g0l) in the 0.06% Nd:YAG EPZS gain module at the laser beam incident angle of 7.1° was obtained around 0.64 for the two OPBD systems mentioned above.
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BMJ Open
December 2024
Department of Sexual and Reproductive Health and Research including UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, World Health Organization, Geneva, Switzerland.
Introduction: Scaling up evidence-based practices (EBPs) in family planning (FP), as recommended by the WHO, has increasingly been accepted by global health actors as core to their mission, goals and activities. National policies, strategies, guidance, training materials, political commitment and donor support exist in many countries to adopt and scale up a range of EBPs, including postpregnancy FP, task sharing for FP and the promotion of social and behaviour change (SBC) for FP. While there has been some success in implementing these practices, coverage remains inadequate in many countries.
View Article and Find Full Text PDFBMJ Open
December 2024
INSERM UMR1231 Génétique des Anomalies du Développement (GAD), Université de Bourgogne, Dijon, France.
Introduction: The megalencephaly capillary malformation polymicrogyria (MCAP syndrome) results from mosaic gain-of-function variants. The main clinical features are macrocephaly, somatic overgrowth, neurodevelopmental delay and brain anomalies. Alpelisib (Vijoice) is a recently FDA-approved PI3Kα-specific inhibitor for patients with PIK3CA-related overgrowth spectrum (PROS).
View Article and Find Full Text PDFNeural Netw
December 2024
CAS Key Laboratory of GIPAS, University of Science and Technology of China, Hefei, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China. Electronic address:
In MARL (Multi-Agent Reinforcement Learning), the trial-and-error learning paradigm based on multiple agents requires massive interactions to produce training samples, significantly increasing both the training cost and difficulty. Therefore, enhancing data efficiency is a core issue in MARL. However, in the context of MARL, agent partially observed information leads to a lack of consideration for agent interactions and coordination from an ego perspective under the world model, which becomes the main obstacle to improving the data efficiency of current proposed MARL methods.
View Article and Find Full Text PDFPhytopathology
January 2025
University of Florida, Microbiology & Cell Science, Cancer/Genetics Research Complex 302, 2033 Mowry Road, Gainesville, Florida, United States, 32610;
(L.) Moench is the fifth most important cereal crop and expected to gain prominence due to its versatility, low input requirements, and tolerance to hot and dry conditions. In warm and humid environments the productivity of sorghum is severely limited by the hemibiotrophic fungal pathogen , the causal agent of anthracnose.
View Article and Find Full Text PDFIndian J Crit Care Med
December 2024
Department of Emergency Medicine, Father Muller Medical College, Mangaluru, Karnataka, India.
Aims And Background: Competency-based medical education has been widely accepted across the globe and it has been adopted in the undergraduate curriculum in India from 2019. One introduction to this curriculum is the Electives postings. Electives are chosen by the students.
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