From the psychological-social point of view, achondroplasia is a complex disorder; in fact, one must take into consideration aspects of the body image, family-surroundings reaction and possible corrective therapy. The achondroplast has a physical image that coincides with his personality and from this standpoint it does not appear to be problematic in the sense that (if accepted right from the start as such) there is a natural acceptance of the disorder, complicated only by the practical difficulties in adapting to a world created for non-achondroplasts. The medieval court jester, who was generally a well-adapted achondroplast, is proof of what we have been saying. The problem of the achondroplast arises when his surroundings, right from the start, reject his disorder, connoting it with destructive anxiety: this seriously harms the subject's physical image, making him an outcast. Even though it is difficult to direct the reaction of the family-surroundings, it is the only way to prevent the achondroplast from suffering greatly and to guarantee the best results from a corrective operation, instead of a renewed rejection.
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http://dx.doi.org/10.1007/978-1-4684-8712-1_56 | DOI Listing |
J Phys Chem A
March 2025
State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.
Identifying atomic-level mechanisms in elemental chemical reactions is crucial for understanding complex reaction processes. This study focuses on the typical multichannel H + NHCl reaction, which plays a significant role in environmental science. High-level ab initio calculations determined seven distinct reaction pathways, leading to three product channels: H + NHCl, HCl + NH, and Cl + NH.
View Article and Find Full Text PDFPoult Sci
March 2025
Department of Animal Science, National Chung Hsing University, Taichung 40227, Taiwan; The iEGG and Animal Biotechnology Center and Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung 40227, Taiwan; i-Center for Advanced Science and Technology (iCAST), National Chung Hsing University, Taichung 40227, Taiwan. Electronic address:
In mammals, tissues other than liver and intestine are known to possess functional MTTP (microsomal triglyceride transfer protein) and apoB (apolipoprotein B) capable of VLDL (very low-density lipoprotein) assembly. Birds are oviparous and possess unique capabilities in lipid biology to accommodate yolk formation through massive deposition of hepatically assembled yolk-targeted VLDLy into ovarian follicles. Following identifications of MTTP and ApoB expression within chicken ovarian stroma, granulosa, theca, and epithelial cells of various classes of follicles, we sought to define the functionality of ovarian MTTP and ApoB in VLDL assembly.
View Article and Find Full Text PDFEchocardiography
March 2025
Department of Physical Therapy, Faculty of Health Science, Kyorin University, Mitaka City, Tokyo, Japan.
Purpose: Central hypovolemia is considered to lead to a compensatory increase in cardiac contractility. From a physiological perspective, left ventricular (LV) twisting motion, which plays an important role in maintaining cardiac output, should be enhanced during central hypovolemia, but previous studies have shown inconsistent findings. Using 3D echocardiography, we tested the hypothesis that the LV twisting and untwisting motion would be enhanced during severe central hypovolemia.
View Article and Find Full Text PDFNeurology
April 2025
Brain Health and Wellness Research Program, St. Michael's Hospital, Unity Health Toronto, Ontario, Canada.
Background And Objectives: Medical clearance for return to play (RTP) after sports-related concussion is based on clinical assessment. It is unknown whether brain physiology has entirely returned to preinjury baseline at the time of clearance. In this longitudinal study, we assessed whether concussed individuals show functional and structural MRI brain changes relative to preinjury levels that persist beyond medical clearance.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
March 2025
From the Department of Orthopaedic Surgery, Boston Medical Center Pl, Boston, MA.
Compartment syndrome is an orthopaedic emergency with moderate-to-severe sequela (pain, muscle contracture, nerve damage, infection, rhabdomyolysis, renal failure, etc.) if inadequately treated and can be difficult to diagnose in a timely fashion. Further complicating timely diagnosis are atypical presentations resulting in compartment syndrome.
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