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Canadian Stroke Best Practice Recommendations: Vascular cognitive impairment, 7th edition practice guidelines update, 2024.
Alzheimers Dement
January 2025
Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
The Canadian Stroke Best Practice Recommendations (CSPR) 7th edition includes this new module on the diagnosis and management of vascular cognitive impairment (VCI) with or without neurodegenerative disease. An expert writing group and people with VCI lived experience (PWLE) reviewed current evidence. Existing recommendations were reviewed and revised, and new recommendations added.
View Article and Find Full Text PDFLactobacillus gasseri prevents ibrutinib-associated atrial fibrillation through butyrate.
Europace
January 2025
Department of Cardiology, the First Affiliated Hospital, Harbin Medical University, Harbin 150001, China.
Ibrutinib, a widely used anti-cancer drug, is known to significantly increase the susceptibility to atrial fibrillation (AF). While it is recognized that drugs can reshape the gut microbiota, influencing both therapeutic effectiveness and adverse events, the role of gut microbiota in ibrutinib-induced AF remains largely unexplored. Utilizing 16S rRNA gene sequencing, fecal microbiota transplantation, metabonomics, electrophysiological examination, and molecular biology methodologies, we sought to validate the hypothesis that gut microbiota dysbiosis promotes ibrutinib-associated AF and to elucidate the underlying mechanisms.
View Article and Find Full Text PDFThe crucial importance of preventive and cardiac rehabilitation programs in patients with atrial fibrillation: AF-CARE units.
Europace
January 2025
Trakya University Faculty of Medicine, Department of Cardiology, Edirne, Turkey.
Long-term pulse pressure trajectories and risk of incident atrial fibrillation: the Tromsø Study.
Eur Heart J
January 2025
Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Background And Aims: Sex-based differences in the association of long-term trends in pulse pressure with future risk of atrial fibrillation (AF) have been explored using data from the population-based Tromsø Study 1986-2016.
Methods: Women (n = 8331) and men (n = 7638) aged ≥20 years who attended at least two of the three Tromsø Study surveys conducted between 1986 and 2001 (the exposure period) were followed up for incident AF throughout 2016 (the follow-up period). Pulse pressure ≥60 mmHg was considered elevated.
Early Versus Late Atrial Fibrillation Recurrence After Pulsed Field Ablation: Insights From the admIRE Trial.
Europace
January 2025
Texas Cardiac Arrhythmia Research Foundation, Austin, TX, USA.
Background And Aims: Studies have shown correlations between early recurrence (ER) and late recurrence (LR) of atrial arrhythmia after ablation with thermal technologies. This admIRE trial (NCT05293639) subanalysis aims to analyze ER versus LR in patients with paroxysmal atrial fibrillation (PAF) undergoing pulsed field ablation (PFA).
Methods: Patients with symptomatic paroxysmal atrial fibrillation and ≥1 transtelephonic monitoring transmission during the blanking period were included (n=169).
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