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Ocular Findings in Pontine Tegmental Cap Dysplasia. | LitMetric

AI Article Synopsis

  • The study focuses on the ocular complications faced by children with pontine tegmental cap dysplasia (PTCD) and the strategies used to manage these issues.
  • A survey conducted with 22 patients or their guardians revealed common eye problems such as neurotrophic cornea, facial palsy, and dry eye syndrome, along with various treatment options like lubricating drops and surgery.
  • Researchers emphasize the importance of awareness and prompt treatment by ophthalmologists to prevent serious vision problems, including corneal damage and blindness in PTCD patients.

Article Abstract

Purpose: To describe the ocular complications experienced by patients with pontine tegmental cap dysplasia (PTCD) and the management strategies used to care for these children.

Methods: Subjects with PTCD were recruited through social media advertisement and completed a survey gathering information on potential ocular problems related to the patient's PTCD disease and any current or previous treatments.

Results: Twenty-two patients or guardians completed the survey. Neurotrophic cornea was the most common ocular diagnosis (82%), followed by facial palsy (59%), dry eye syndrome (59%), and blepharitis (55%). Other diagnoses included cortical visual impairment (27%), strabismus (27%), amblyopia (18%), and nystagmus (18%). Common treatment modalities included lubricating eye drops (59%) or ointment (50%), contact lenses (14%), punctal plugs (27%), glasses (45%), and patching (18%). The most common surgical interventions were temporary or permanent tarsorrhaphy (64%) and amniotic membrane grafts (23%). In total, 68% of families reported self-injury to eyes and 91% reported the child to be primarily a visual learner.

Conclusions: PTCD is a newly described, very rare disorder with a variety of vision-threatening ocular manifestations. It is essential that the ophthalmologist be aware of the potential for neurotrophic cornea because timely treatment could prevent corneal scarring, perforation, and blindness.

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Source
http://dx.doi.org/10.1097/ICO.0000000000002361DOI Listing

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