AI Article Synopsis
- Cell migration research is a rapidly growing field, but current datasets are underutilized due to varying experimental methods and formats that hinder data sharing and analysis.
- Making these datasets findable, accessible, interoperable, and reusable (FAIR) would enhance opportunities for meta-analysis and data integration.
- The Cell Migration Standardisation Organisation (CMSO) is working to establish standardized formats and vocabularies for cell migration data, which will improve algorithms, tools, and enable further exploration of this complex biological process.
Article Abstract
Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317087 | PMC |
| http://dx.doi.org/10.1093/gigascience/giaa041 | DOI Listing |
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