iPTMnet is a bioinformatics resource that integrates protein post-translational modification (PTM) data from text mining and curated databases and ontologies to aid in knowledge discovery and scientific study. The current iPTMnet website can be used for querying and browsing rich PTM information but does not support automated iPTMnet data integration with other tools. Hence, we have developed a RESTful API utilizing the latest developments in cloud technologies to facilitate the integration of iPTMnet into existing tools and pipelines. We have packaged iPTMnet API software in Docker containers and published it on DockerHub for easy redistribution. We have also developed Python and R packages that allow users to integrate iPTMnet for scientific discovery, as demonstrated in a use case that connects PTM sites to kinase signaling pathways.
Background: Stability during early postnatal life in preterm infants is related to better outcomes. Although vital signs are monitored continuously in Neonatal Intensive Care Unites, this monitoring does not include all physiological parameters nor data such as movement patterns. Although there are scattered sources of data, there is no centralized data hub for neonates information.
EnteroBase is a web-based platform that offers curated databases of genome sequences from over 1.1 million bacterial isolates, including notable pathogens like Streptococcus and Mycobacterium tuberculosis.
The platform now features tools for detecting antimicrobial resistance and a new bubble plot tool for visualizing bacterial genomic structures.
Enhanced access and functionalities are provided through a user-friendly interface and a RESTful API, with ongoing development by an international consortium to improve and maintain the system.
The advent of artificial intelligence has positively transformed many areas of our lives, including the medical field. In this article, we propose the development of a medical diagnosis chatbot based on patients' symptoms, using artificial intelligence as an innovative solution. The aim of this tool is to provide doctors with a preliminary diagnosis based on the symptoms presented by patients.
The interoperability of healthcare data across various systems remains a big challenge, largely attributable to the disparate data schemas and APIs in use. This study showcases the integration of a FHIR layer into GameBus, a gamified health platform, aiming to enhance its interoperability. Traditionally, GameBus has relied on proprietary data schemas and REST APIs, which restricted data exchange with other platforms.
The European Bioinformatics Institute (EMBL-EBI)'s Job Dispatcher framework provides access to a wide range of core databases and analysis tools that are of key importance in bioinformatics. As well as providing web interfaces to these resources, web services are available using REST and SOAP protocols that enable programmatic access and allow their integration into other applications and analytical workflows and pipelines. This article describes the various options available to researchers and bioinformaticians who would like to use our resources via the web interface employing RESTful web services clients provided in Perl, Python, and Java or who would like to use Docker containers to integrate the resources into analysis pipelines and workflows.
