Objective: The most common form of measurement of breath alcohol content (BrAC) is through the use of a diode catheter. This study aims to test the accuracy of breath alcohol analysis through different manipulations.
Methods: BrAC was measured after individuals consumed each standardized beer until they reached a 0.1 BrAC. Then, the individuals were breath analyzed while not providing full effort, using the side of their mouths, immediately after hyperventilating, 5 and 10 min after hyperventilation, immediately after a sip of water, and 5 min after that water.
Results: There were 54 individuals. Two baselines were used as the controls. The first baseline was a mean BrAC of. 104 with standard deviation of +0.008 for poor effort, side of mouth, and hyperventilating. The second baseline used for drinking water manipulations was a BrAC of 0.099 + 0.11. Poor effort (mean + standard deviation: 0.099 ± 0.10, < 0.0001), immediately after hyperventilating (0.086 ± 0.011, < 0.0001), 5 min after hyperventilating (0.099 ± 0.009, < 0.0001), and 10 min after hyperventilating (0.099 ± 0.011, < 0.0001) were all found to be statistically significant in their ability to lower BrAC. Both immediately after water (0.084 ± 0.011, < 0001) and 5 min after drinking water (0.096 ± 0.13, < 0.0001) were found to have significantly altered the BrAC.
Conclusion: Our research shows that manipulations can alter BrAC readings significantly. Breath analyzer operators should be cognizant of these methods that may lead to falsely lower BrAC readings.
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http://dx.doi.org/10.4103/JETS.JETS_4_19 | DOI Listing |
Fed Pract
October 2024
Veterans Affairs Boston Healthcare System, West Roxbury, Massachusetts.
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January 2025
Division of Anesthesia Critical care, Emergency and Pain Medicine, University Hospital Centre Nimes, Nimes, Occitanie, France.
Introduction: Intensive care unit (ICU) patients under mechanical ventilation experience mild-to-severe pain. International guidelines emphasise the importance and benefits of multimodal analgesia to minimise opioid consumption and its side effects. However, no recommendation about drugs or protocol has been formulated.
View Article and Find Full Text PDFSci Rep
January 2025
Institute for Breath Research, University of Innsbruck, Innrain 80/82, Innsbruck, 6020, Austria.
Cytochrome P450 (CYP) 3A4 plays a major role in drug metabolism. Its activity could be determined by non-invasive and cost-effective assays, such as breath analysis, for the personalised monitoring of drug response. For the first time, we identify an isotopically unlabelled CYP3A4 substrate, tolterodine that leads to the formation of a non-toxic volatile metabolite, acetone, which could potentially be applied to monitor CYP3A4 activity in humans.
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January 2025
Universidade Federal de Mato Grosso do Sul - UFMS, Programa de Pós-graduação em Ciência Animal, Campo Grande, MS, Brasil.
This study evaluated the use of the essential oil of Lippia origanoides (EOLO) as an anesthetic for juvenile pacu, Piaractus mesopotamicus. Two experiments were performed. In Experiment I, anesthetic induction and recovery times and ventilatory frequency (VF) were determined for fish (n= 48; 29.
View Article and Find Full Text PDFSci Rep
January 2025
Biomedical Engineering Department, Faculty of Engineering, Helwan University, Cairo, Egypt.
Car accidents, infections caused by bacteria or viruses, metastatic lesions, tumors, and malignancies are the most frequent causes of chest wall damage, leading to the removal of the affected area. After excision, artificial bone or synthetic materials are used in chest wall reconstruction to restore the skeletal structure of the chest. Chest implants have traditionally been made from metallic materials like titanium alloys due to their biocompatibility and durability.
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