Selecting (inter-varietal) for tolerance to metal-contamination has been proposed as a strategy to develop superior genotypes for phytoextraction of lead (Pb) through selection and breeding techniques. To understand the differences among accessions of a single species to Pb accumulation, a pot experiment was conducted with three accessions under levels of Pb added to the soil (0, 90, 180, and 540 mg kg). The duration of the growth period was 100 d. Pb concentration levels did not affect the flowering of accessions. Plant height, shoot dry matter, and root dry matter were reduced linearly when soil Pb concentration increased to 540 mg kg. A significant interaction between Pb concentration levels and accessions was observed for Pb concentration in shoots and roots, indicating genotypic variation in Pb absorption. The concentration of Pb in shoots in accession PI 180266 was 51% higher compared to accessions PI 649105 and PI 432379 when soil Pb concentration increased to 540 mg kg. It can be concluded that the accessions differed significantly in Pb uptake, and the selection of tolerant cultivars might be helpful for Pb phytoremediation of contaminated soils.
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http://dx.doi.org/10.1080/15226514.2020.1759506 | DOI Listing |
Biomark Med
January 2025
Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Zhuhai, China.
Objective: This study aims to explore the association between arginase 1 (ARG1) genetic variation and susceptibility to type 2 diabetes (T2DM) vascular complications, a primary cause of morbidity and mortality in diabetics.
Methods: ARG1, a risk gene for cardiovascular disease, was identified from GEO datasets GSE22255 and GSE58294. The ENCODE database identified four candidate single-nucleotide polymorphism (SNP) loci.
Hum Genomics
January 2025
Department of Biology, Tor Vergata University of Rome, Via della Ricerca Scientifica 1, 00133, Rome, Italy.
Background: The Immunoglobulin Heavy Chain (IGH) genomic region is responsible for the production of circulating antibodies and warrants careful investigation for its association with COVID-19 characteristics. Multiple allelic variants within and across different IGH gene segments form a limited set of haplotypes. Previous studies have shown associations between some of these haplotypes and clinical outcomes of COVID-19.
View Article and Find Full Text PDFBMC Pediatr
January 2025
Department of Orthodontics, University Hospital Bonn, Medical Faculty, Welschnonnenstr. 17, 53111, Bonn, Germany.
Background: Children with non-syndromic cleft lip with or without palate (CL ± P) may present alterations in dental development. The purpose of this cross-sectional study was to compare the dental age (DA) between children with and without CL ± P, and whether single nucleotide polymorphisms (SNPs) in genes encoding growth factors are associated with DA variations.
Methods: Children aged between 5 and 14 years with and without CL ± P were recruited to participate in this study.
BMC Genomics
January 2025
Department of Population Health and Reproduction, Davis School of Veterinary Medicine, University of California, Room 4206 Vet Med3A One Shields Ave, Davis, CA, 95616, USA.
Background: Allele-specific expression (ASE) analysis provides a nuanced view of cis-regulatory mechanisms affecting gene expression.
Results: An equine ASE analysis was performed, using integrated Iso-seq and short-read RNA sequencing data from four healthy Thoroughbreds (2 mares and 2 stallions) across 9 tissues from the Functional Annotation of Animal Genomes (FAANG) project. Allele expression was quantified by haplotypes from long-read data, with 42,900 allele expression events compared.
BMC Plant Biol
January 2025
Institute of Biology, Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, Neuchâtel, Switzerland.
Background: Upland cotton (Gossypium hirsutum) plants constitutively store volatile terpenes in their leaves, which are steadily emitted at low levels. Herbivory leads to a greater release of these stored volatiles. Additionally, damaged plants increase the accumulation of volatile terpenes in their leaves and begin to synthesize and emit other terpenes and additional compounds.
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