AI Article Synopsis
- Recent studies by Beaulieu-Laroche et al. and Gidon et al. provide the first patch-clamp recordings from the dendrites of human neocortical neurons.
- These recordings reveal that human dendrites can generate backpropagating action potentials and fast calcium spikes, indicating they are electrically excitable.
- The findings suggest there may be significant differences in how dendrites function across different species, which could impact our understanding of brain computation.
Article Abstract
The first patch-clamp recordings from the dendrites of human neocortical neurons have recently been reported by Beaulieu-Laroche et al. and Gidon et al. These studies have shown that human dendrites are electrically excitable, exhibiting backpropagating action potentials and fast dendritic calcium spikes. This new frontier highlights the potential for interspecies differences in the biophysics of dendritic computation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903140 | PMC |
| http://dx.doi.org/10.1016/j.tics.2020.03.002 | DOI Listing |
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