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http://dx.doi.org/10.1002/jmv.25997 | DOI Listing |
Microbes Infect
December 2024
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA. Electronic address:
Cystic fibrosis (CF) is an autosomal recessive genetic disorder characterized by impairment of the CF transmembrane conductance regulator (CFTR) via gene mutation. CFTR is expressed at the cellular membrane of epithelial cells and functions as an anion pump which maintains water and salt ion homeostasis. In pulmonary airways of CF patients, pathogens such as P.
View Article and Find Full Text PDFVet Immunol Immunopathol
January 2025
Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, Jiangsu 225009, China; Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of Agriculture of China, Yangzhou University, Yangzhou, Jiangsu 225009, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, Jiangsu 225009, China; Joint International Research Laboratory of Agriculture and Agri-product Safety of the Ministry of Education, Yangzhou University, Yangzhou, Jiangsu 225009, China. Electronic address:
African swine fever (ASF) is a transmissible and deadly viral disease caused by the African swine fever virus (ASFV) that has considerably affected the global pig industry. Vaccination is considered a potentially effective method to control ASF. However, live attenuated vaccines can't protect against all circulating virus isolates.
View Article and Find Full Text PDFFish Shellfish Immunol
February 2025
College of Life Sciences, Liaoning Normal University, Dalian, China; Lamprey Research Center, Liaoning Normal University, Dalian, China. Electronic address:
The lamprey serves as a key model organism for studying the origin and evolution of species, embryonic development, and the immune system. The immune system primarily relies on pattern recognition receptors, including Toll-like receptors (TLRs), with Toll-like receptor 5 (TLR5) having a particularly complex evolutionary history. Currently, although TLR5 is being identified in an expanding array of taxonomic groups, a comprehensive study on its evolutionary aspects is yet to be conducted.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Department Biomolecular Health Sciences, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, the Netherlands.
The increase of Arcobacter spp. infection cases in humans, coupled with varying symptomatology, highlights the need to study the virulence mechanisms of these bacteria. Arcobacter butzleri can induce the release of several proinflammatory cytokines in human monocytic-derived macrophages, but the mechanism used to achieve this is still unclear.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Department of Animal Sciences, School of Life Sciences, Central University of Himachal Pradesh, District Kangra, Himachal Pradesh, India, 176206. Electronic address:
Coxiella burnetii (Cbu) is the gram-negative intracellular pathogen responsible for deadly zoonotic infection, Q fever. The pathogen is environmentally stable and distributed throughout the world which is sustained in nature by chronic infection of ruminants. The epidemiological studies on Q fever indicates it as emerging public health problem in various countries and it is imperative to promptly identify an appropriate therapeutic solution for this pathogen.
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