Background: In South Africa's National Health Laboratory Service, ad hoc mean turn-around time (TAT) reporting is an important indicator of performance. However, historic static TAT reporting did not assess very long or very short times. An interactive TAT dashboard was developed using the following TAT measures; (1) median, (2) 75th percentile and (3) percentage of within cut-off TAT to allow for improved differentiation of TAT performance.
Objectives: The objective of our study was to demonstrate increased efficiency achieved by using an interactive TAT dashboard.
Methods: A retrospective descriptive study design was used. Creatinine TAT outcomes were reported over 122 weeks from a high-volume laboratory in Gauteng, South Africa. The percentage of within cut-off and 75th percentile TAT were analysed and reported using Microsoft Excel. A focus group session was used to populate a cause and effect diagram.
Results: The percentage of within cut-off TAT increased from 10% in week 4 to 90% and higher from week 81. The 75th percentile decreased from 10 hours in week 4 to under 5 h from week 71. Component TAT analysis revealed that the 75th percentile testing was 5 h or longer for weeks 4, 5 and 48. The 75th percentile review TAT ranged from 1 h to 15 h. From week 41, the review TAT was under 1 h.
Conclusion: Our study demonstrated that the use of an interactive TAT dashboard coupled with good management can dramatically improve TAT and efficiency in a high-volume laboratory.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203269 | PMC |
http://dx.doi.org/10.4102/ajlm.v9i2.948 | DOI Listing |
Am J Perinatol
January 2025
Pediatrics, Duke University Health System, Durham, United States.
Objective: To characterize the cerebrospinal fluid (CSF) of infants with stroke and compare those findings to the CSF of infants with bacterial meningitis and neither condition in the first 14 postnatal days.
Study Design: Cohort study of 30,092 infants who received a lumbar puncture in the first 14 postnatal days discharged from >300 neonatal intensive care units from 1997-2020. CSF parameters were compared between infants with stroke and bacterial meningitis using non-parametric hypothesis testing and quantile regression.
Sleep Med
January 2025
Université de Paris-Cité, AP-HP, Hôpital Robert Debré, Service de Physiologie Pédiatrique-Centre du Sommeil, INSERM NeuroDiderot, F-75019, Paris, France. Electronic address:
Study Objectives: It is unknown whether loudness of snoring or hypoxic burden are related to higher hyperactivity scores in habitually snoring children and whether this effect is impacted by the severity of sleep-disordered breathing (SDB). This study investigates the prevalence of hyperactivity in children with habitual snoring and the independent effects of loudness of snoring, as reported by the parents, hypoxic burden and obstructive sleep apnea syndrome's severity (OSAS) on hyperactivity, as measured by the Conners' Parent Rating Scale-Hyperactivity Index (CPRS-HI).
Methods: Children with habitual snoring aged 3-18 years were recruited for an overnight polysomnography reporting apnea-hypopnea index (AHI) and hypoxic burden, acoustic rhinometry, clinical examination and parental questionnaires assessing snoring loudness and CPRS-HI.
J Assist Reprod Genet
January 2025
Department of Obstetrics and Gynaecology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.
Purpose: To assess the association of serum vitamin D level and the live birth rate in women undergoing frozen embryo transfer (FET).
Methods: This is a retrospective cohort study involving 1489 infertile women who had frozen embryo transfer at two tertiary reproductive medicine centres from 2019 to 2021. Only the first frozen embryo transfer was included for women who had repeated transfers during the period.
Alzheimers Dement
December 2024
Erasmus University Medical Center, Rotterdam, Zuid-Holland, Netherlands.
Background: Non-steroidal anti-inflammatory (NSAID) medication are suggested to have beneficial effects in the prevention of Alzheimer's disease, due to anti-inflammatory and possibly amyloid-lowering properties. However, the results of observational studies and randomized-controlled trials have been inconsistent, and duration and dose-response relationships are still unclear.
Method: We included 11,745 dementia-free participants from the prospective population-based Rotterdam Study (59.
Alzheimers Dement
December 2024
University of Maryland School of Public Health, College Park, MD, USA.
Background: Escalating drug costs are likely to disproportionately burden individuals with Alzheimer's disease and related dementias (ADRD) as they often have multiple chronic conditions (MCC). This study aimed to estimate the incremental total and out-of-pocket (OOP) drug costs associated with ADRD and MCC across the drug cost distributions.
Method: The study used a nationally representative cross-sectional dataset from 2003 to 2021 Medical Expenditure Panel Survey.
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