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Lack of effect of renal function on uptake of 99mTc-sestamibi in renal masses.
Nucl Med Commun
January 2025
Molecular Imaging and Therapeutics, Department of Radiology, University of North Carolina, Chapel Hill, North Carolina.
Objective: The appropriate clinical management of indeterminate small renal masses can be improved based on accurate risk stratification. This study aimed to investigate the impact of renal function on the uptake of technetium-99m (99mTc)-sestamibi, a widely available imaging agent that can be utilized to identify oncocytomas and other benign/indolent renal masses.
Methods: A retrospective cohort study was conducted, involving 100 consecutive patients who underwent 99mTc-sestamibi single-photon emission computed tomography/computed tomography.
Utility of a C-Spirulina Stable Isotope Gastric Emptying Breath Test in Diabetes Mellitus.
Neurogastroenterol Motil
January 2025
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The carbon-13 spirulina gastric emptying breath test (GEBT) is approved to identify delayed, but not accelerated, gastric emptying (GE). We compared the utility of the GEBT to scintigraphy for diagnosing abnormal GE in patients with diabetes mellitus.
Methods: Twenty-eight patients with diabetes ate a 230-kcal test meal labeled with technetium 99 m and C-spirulina, after which 10 scintigraphic images and breath samples (baseline, 15, 30, 45, 60, 90, 120, 150, 180, 210, and 240 min) were collected on 2 occasions 1 week apart.
Hypoperfusion of the Left Insula, Operculum, and Putamen on Technetium-99m Ethyl Cysteinate Dimer (99mTc-ECD) Single-Photon Emission Computed Tomography in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease.
Cureus
November 2024
Department of Neurology, Tottori University, Yonago, JPN.
Article Synopsis
- eZIS effectively analyzes brain blood flow patterns, revealing reduced cerebral blood flow in key areas for patients with forgetfulness.
- SPECT imaging compared patients with mild cognitive impairment (MCI) and early Alzheimer's disease (AD) to controls, uncovering significant differences in blood flow.
- The study's findings highlight the left insula, operculum, and putamen as critical regions, though the broader implications for clinical treatment remain uncertain.
The Role of Lung Ventilation/Perfusion Scan in the Management of Chronic Thromboembolic Pulmonary Hypertension.
Nucl Med Mol Imaging
December 2024
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, Republic of Korea 05505.
Article Synopsis
- * The ventilation/perfusion (V/Q) scan is the best imaging method for detecting CTEPH because it is more sensitive than CT pulmonary angiography, though its results may differ from those seen in acute PE cases.
- * Recent advancements show that combining V/Q scans with SPECT or SPECT/CT improves diagnostic accuracy, which helps in early detection and better treatment outcomes for patients with CTEPH.
Simplified dual-time-point Tc-pyrophosphate scintigraphy in patients with suspected transthyretin amyloid cardiomyopathy: A single center series.
J Formos Med Assoc
October 2024
Department of Nuclear Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan; Division of Cardiology, Cardiovascular Medical Center, Far Eastern Memorial Hospital, New Taipei City, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Graduate Institute of Medicine, Yuan Ze University, Taoyuan, Taiwan. Electronic address:
Background There is a lack of consensus regarding the optimal imaging time points and imaging techniques between planar and/or single-photon emission computed tomography (SPECT)/computed tomography (CT) acquisitions for technetium-99 m pyrophosphate (99mTc-PYP) cardiac scintigraphy. The aim of this study was to investigate correlations between planar and SPECT/CT images and between 1-h and 3-h imaging time points. Methods We retrospectively analyzed consecutive patients with clinically suspected transthyretin amyloid cardiomyopathy who underwent 99mTc-PYP scintigraphy from November 1, 2019 to November 30, 2022.
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