Endocytosis plays critical roles in cellular processes, including nutrient uptake and signal transduction. Ede1 is an endocytic scaffolding protein that contributes to endocytic site initiation and maturation in yeast. However, the functions of Ede1 in phytopathogenic fungi are not known. Here, we identified functions of FgEde1 (FGSG_05182) in Fusarium graminearum. Deletion of FgEde1 resulted in defects in hyphal growth, conidiation and ascospore development. The FgEde1 deletion mutant showed reduced deoxynivalenol (DON) production and virulence in wheat. Furthermore, the FgEde1 deletion mutant also exhibited increased resistance to osmotic and oxidative stress as well as cell-wall perturbing agents. Importantly, deletion of FgEde1 increased the severity of autophagy in hyphae. Taken together, these results reveal that FgEde1 is involved in hyphal growth, asexual and sexual reproduction, virulence, stress responses, and autophagy in F. graminearum.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fgb.2020.103400 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of qPCR methods to detect and quantify the novel Fusarium graminearum 3ANX chemotype variant.
J Microbiol Methods
January 2025
Charlottetown Research and Development Centre, Agriculture and Agri-Food Canada, 440 University Avenue, Charlottetown, PE C1A 4N6, Canada. Electronic address:
The devastating plant pathogen Fusarium graminearum produces mycotoxins including the novel 3ANX toxin. To detect 3ANX-producing isolates, SYBR Green and locked nucleic acid probe assays were developed, targeting 3ANX Tri1 polymorphisms. Assays were efficient with R > 0.
View Article and Find Full Text PDFFungal Pathogen Diversity and Fungicide Resistance Assessment in Fusarium Crown Rot of Wheat in the Huanghuai Region of China.
J Agric Food Chem
January 2025
State Key Laboratory of Rice Biology and Breeding, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.
Fusarium crown rot (FCR) poses a major threat to wheat production in the Huanghuai wheat region of China. This study aims to enhance understanding of pathogen populations causing FCR, focusing on their pathogenicity, trichothecene genotypes, and fungicide resistance. During the 2022-2023 growing seasons, we collected 1820 fungal isolates from 233 locations in this region.
View Article and Find Full Text PDFDeletion of FgAtg27 decreases the pathogenicity of Fusarium graminearum through influence autophagic process.
Int J Biol Macromol
January 2025
Engineering Research Center of Ecology and Agricultural Use of Wetland, Ministry of Education, MARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), Hubei Engineering Research Center for Pest Forewarning and Management, College of Agriculture, Yangtze University, Jingzhou 434025, Hubei, China. Electronic address:
Autophagy is a conserved and unique degradation system in eukaryotic cells, which plays crucial roles in the growth, development and pathogenesis of Fungi. Despite that, it is poorly understood in Fusarium graminearum currently. Here, we identified an autophagy gene FgAtg27 from F.
View Article and Find Full Text PDFTriple Threat: How Global Fungal Rice and Wheat Pathogens Utilize Comparable Pathogenicity Mechanisms to Drive Host Colonization.
Mol Plant Microbe Interact
January 2025
University of Florida, Microbiology and Cell Science, Gainesville, Florida, United States;
Plant pathogens pose significant threats to global cereal crop production, particularly for essential crops like rice and wheat, which are fundamental to global food security and provide nearly 40% of the global caloric intake. As the global population continues to rise, increasing agricultural production to meet food demands becomes even more critical. However, the production of these vital crops is constantly threatened by phytopathological diseases, especially those caused by fungal pathogens such as , the causative agent of rice blast disease, , responsible for head blight (FHB) in wheat, and , the source of Septoria tritici blotch (STB).
View Article and Find Full Text PDFThe Synergy of Chitosan and Azoxystrobin Against Is Modulated by Selected ABC Transporters.
Int J Mol Sci
December 2024
Plant Breeding and Acclimatization Institute-National Research Institute, Radzikow, 05-870 Blonie, Poland.
Article Synopsis
- Innovative strategies are needed to combat fungal pathogens for sustainable crop protection, with traditional fungicides facing resistance issues due to their single-target action.
- The study investigated the synergistic effects of chitosan (CS) and the fungicide azoxystrobin, finding a high synergy score that significantly improves antifungal efficacy.
- Additionally, combining CS and azoxystrobin with RNA interference techniques enhanced fungal control, highlighting a promising eco-friendly approach and the need for further research on its molecular mechanisms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!