AI Article Synopsis
- * It compared raw and processed samples that were cooked using black bean juice, revealing that the steamed samples reduced RANKL expression while increasing several important bone-related proteins such as osteoprotegerin and alkaline phosphatase.
- * The findings suggest that these processed items could serve as a potential alternative treatment for various bone-related conditions like osteoporosis and periodontitis.
Article Abstract
This present study evaluated the effects of processed on osteogenesis using Sarcoma osteogenic (SaOS-2) cell lines and osteoclastogenesis of bone marrow-derived macrophage cells (BMM) and to elucidate differences in effect on the expression of bone-related proteins between commercially sold and patented, -propagated Korea Institute of Oriental Medicine (KIOM) . Raw and that were stir-baked and steamed in black bean juice were compared, and western blotting analysis was performed to investigate the expression of bone remodeling-related proteins in SaOS-2 cells. In the cells treated with steamed in black bean juice, the expression of RANKL was decreased, whereas that of osteoprotegerin, alkaline phosphatase, Runx2, and osterix was increased. Owing to these results, we conclude that processed can be used as an alternative treatment for bone diseases such as osteoporosis, osteopenia, periodontitis, and Paget's disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196996 | PMC |
| http://dx.doi.org/10.1155/2020/4168535 | DOI Listing |
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