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Clinical Feasibility of Deep Learning-Based Attenuation Correction Models for Tl-201 Myocardial Perfusion SPECT.
Clin Nucl Med
May 2024
Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine, Suwon, South Korea.
Purpose: We aimed to develop deep learning (DL)-based attenuation correction models for Tl-201 myocardial perfusion SPECT (MPS) images and evaluate their clinical feasibility.
Patients And Methods: We conducted a retrospective study of patients with suspected or known coronary artery disease. We proposed a DL-based image-to-image translation technique to transform non-attenuation-corrected images into CT-based attenuation-corrected (CT AC ) images.
Comparison between multiple logistic regression and machine learning methods in prediction of abnormal thallium scans in type 2 diabetes.
World J Clin Cases
November 2023
Department of Cardiology, Fu Jen Catholic University Hospital, New Taipei City 24352, Taiwan.
Background: The prevalence of type 2 diabetes (T2D) has been increasing dramatically in recent decades, and 47.5% of T2D patients will die of cardiovascular disease. Thallium-201 myocardial perfusion scan (MPS) is a precise and non-invasive method to detect coronary artery disease (CAD).
View Article and Find Full Text PDFMyocardial Flow Assessment After Heart Transplantation Using Dynamic Cadmium-Zinc-Telluride Single-Photon Emission Computed Tomography With Tl and Tc Tracers and Validated by N-NH Positron Emission Tomography.
Circ Cardiovasc Imaging
June 2023
Institute of Environmental and Occupational Health Sciences (M.-F.C.), National Taiwan University, Taipei.
Background: Cardiac allograft vasculopathy (CAV) is an obliterative and diffuse form of vasculopathy and is the most common cause of long-term cardiovascular mortality in heart transplant patients. This study aimed to investigate the diagnostic performance of Tc and Tl tracers in the assessment of CAV using cadmium-zinc-telluride (CZT) single-photon emission computed tomography (SPECT) for myocardial blood flow (MBF) and myocardial flow reserve (MFR) quantification, which was further validated using N-NH positron emission tomography (PET).
Methods: Thirty-eight patients with prior heart transplantation who underwent CZT SPECT and N-NH PET dynamic scans were included in this study.
Association of Long Noncoding RNA Expression Signatures with Stress-Induced Myocardial Perfusion Defects.
Biomolecules
May 2023
Integrated Precision Health and Immunodiagnostic Center, Department of Laboratory Medicine, China Medical University Hsinchu Hospital, Zhubei City 302, Taiwan.
Stress-induced myocardial perfusion defects found in dipyridamole-thallium-201 single-photon emission computed tomography imaging may indicate vascular perfusion abnormalities and risk of obstructive or nonobstructive coronary heart disease. Besides nuclear imaging and subsequent coronary angiography (CAG), no blood test can indicate whether dysregulated homeostasis is associated with stress-induced myocardial perfusion defects. This study investigated the expression signature of long noncoding RNAs (lncRNAs) and genes involved in vascular inflammation and stress response in the blood of patients with stress-induced myocardial perfusion abnormalities ( = 27).
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