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Primary healthcare's carbon footprint and sustainable strategies to mitigate its contribution: a scoping review.
BMC Health Serv Res
December 2024
School of Pharmacy & Biomolecular Sciences, University of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Background: The escalating climate crisis poses a significant threat to global public health. The healthcare sector, designed to protect human health is a major contributor to greenhouse gas emissions, and thus, a key driver of climate degradation. This paradox endangers both planetary and human health, making the decarbonization of healthcare, including primary care, critical.
View Article and Find Full Text PDFDNA sequence-induced solid phase transition as a solution to the genome folding paradox.
Res Sq
December 2024
Department of Biochemistry and Molecular Biophysics, Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.
Ultra long-range genomic contacts, which emerge as prominent components of genome architecture, constitute a biochemical paradox. This is because regulatory DNA elements make selective and stable contacts with DNA sequences located megabases away, instead of interacting with proximal sequences occupied by the same exact transcription factors (TF). This is exemplified in olfactory sensory neurons (OSNs), where only a fraction of Lhx2/Ebf1/Ldb1-bound sites interact with each other, converging into highly selective multi-chromosomal enhancer hubs.
View Article and Find Full Text PDFIdentifying the impact of local connectivity patterns on dynamics in excitatory-inhibitory networks.
ArXiv
November 2024
Laboratoire de Neurosciences Cognitives et Computationnelles, INSERM U960.
Networks of excitatory and inhibitory (EI) neurons form a canonical circuit in the brain. Seminal theoretical results on dynamics of such networks are based on the assumption that synaptic strengths depend on the type of neurons they connect, but are otherwise statistically independent. Recent synaptic physiology datasets however highlight the prominence of specific connectivity patterns that go well beyond what is expected from independent connections.
View Article and Find Full Text PDFFactors Associated With Pregnancy and Childbirth Among Married Couples: A Longitudinal Analysis Using the 2012-2018 Korean Health Panel.
Cureus
October 2024
Department of Health and Medical Information, Myongji College, Seoul, KOR.
Introduction: South Korea is experiencing a demographic paradox of the lowest birth rate worldwide with the longest life expectancy. Many studies on pregnancy and childbirth primarily focused on women's factors, often overlooking the contribution of both spouses. However, men also play a vital role in creating an environment for bearing and raising children.
View Article and Find Full Text PDFMRI changes in cryptococcal meningoencephalitis exacerbated by antifungal treatment due to post-infectious inflammatory syndrome: A case report.
Radiol Case Rep
December 2024
Department of Radiology, Shin-Kuki General Hospital, , 418-1 Kamihayami, Kuki City, Saitama Prefecture 346-8530.
Cryptococcal meningitis is one of the most common fungal meningitis in adults and causes disabling morbidity and mortality worldwide. The occurrence of postinfectious inflammatory response syndrome during cryptococcal meningitis treatment presents a diagnostic challenge. This time course seems paradoxical because patients show worsening symptoms and imaging findings.
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