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Palliative Care Spiritual Assessment and Goals-of-Care Discussions in the Neurocritical Care Unit: Collaborating with Chaplains.
Neurocrit Care
January 2025
Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA.
Introduction: Neuropalliative care is an emerging subspecialty of palliative care designed to address the unique supportive care needs of patients with serious neurological illness, including those receiving neurocritical care in intensive care units. Spiritual care is a vital component in the provision of holistic and humanized care to these patients. A chaplain who is specially trained and credentialed in care for those with serious illness is the health care professional responsible for making spiritual assessments and contributes to the plan of care, facilitating decision making, and guiding other clinicians in the provision of generalist spiritual care.
View Article and Find Full Text PDFIncidence of Guillain-Barré syndrome in Cuba before and during the Oropouche virus emergency, 2018-2024.
J Neurol
January 2025
Research, Diagnosis and Reference Center, PAHO/WHO Collaborating Center for the Study of Dengue and Its Control, Institute "Pedro Kourí", Havana, Cuba.
YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates.
Sci Rep
January 2025
Barcelona Institute for Global Health (ISGlobal, Hospital Clínic-University of Barcelona), Rosselló 149-153, Barcelona, 08036, Spain.
We recently characterized the potent antiplasmodial activity of the aggregated protein dye YAT2150, whose presumed mode of action is the inhibition of protein aggregation in the malaria parasite. Using single-dose and ramping methods, assays were done to select Plasmodium falciparum parasites resistant to YAT2150 concentrations ranging from 3× to 0.25× the in vitro IC of the compound (in the two-digit nM range) and performed a cross-resistance assessment in P.
View Article and Find Full Text PDFPrevalence, Diagnosis, and Management of Stress Urinary Incontinence in Women: A Collaborative Review.
Eur Urol
January 2025
Department of Urology, Freeman Hospital Newcastle-upon-Tyne UK; Translational and Clinical Research Institute, Newcastle University Newcastle-upon-Tyne UK.
Background And Objective: Stress urinary incontinence (SUI), defined as any involuntary leakage of urine associated with physical activity, remains underdiagnosed and undertreated. This review aims to provide an updated overview of the prevalence, diagnosis, and treatment of SUI in women, drawing upon recent evidence-based literature and clinical guidelines.
Methods: A systematic search of the MEDLINE database was conducted to identify only the most up-to-date and relevant studies published up to February 26, 2024, including the reference ESTER systematic review.
Association between symptom characteristics and disease severity in patients suspected of coronary artery disease.
J Cardiovasc Comput Tomogr
January 2025
Department of Cardiology, Gødstrup Hospital, Herning, Denmark.
Background: Discrepancies often exist between patient-reported symptoms and diagnostic test findings in patients with suspected obstructive coronary artery disease (CAD).
Objectives: To quantify the association between patient-reported symptoms and the diagnosis of severe stenosis in patients with suspected obstructive CAD.
Methods: Two large-scale cohorts of patients with new-onset symptoms suggestive of obstructive CAD were evaluated.
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