Virtual resection of liver structures guided by three-dimensional visualization technology (3DVT) has been extensively used in China. This technique provides a safe and effective method for accurate diagnosis of liver tumors and has important applications in preoperative evaluation, surgical planning and intraoperative guidance of liver cancer surgeries. The technical advantages and clinical significance of 3DVT in the diagnosis and treatment of complex liver tumors have been recognized. In order to standardize the application of 3DVT in the precision diagnosis and treatment of complex liver tumors, this guideline provides explanations and recommendations in the following aspects: (1) the establishment of homogenization processing and quality control system of 3D reconstruction; (2) the establishment of 3D reconstructed models of abdominal organs and lesions; (3) the individualized classification and quantitative analysis of blood vessels based on 3DVT; (4) 3DVT-based classification and grading of hepatic vessels in complex hepatic tumors; (5) evaluation system for surgery evaluation after reconstruction of the 3D visualization model; (6) application of 3D printing in complex hepatectomy; (7) virtual reality technology; (8) ICG fluorescence imaging; (9) multi-modal images for real-time navigation; (10) three-dimensional visualization to guide the preoperative surgical planning of precision hepatectomy; (11) application of 3DVT guidance in other therapeutic methods of hepatocellular carcinoma; (12) application of 3DVT in follow-up evaluation of the patients after liver cancer surgeries. 3DVT for visualization of the liver structures has important clinical values for accurate preoperative evaluation, preoperative planning and surgical navigation of complex liver tumors, and it facilitates precision surgeries to improve the outcomes and promote postoperative recovery of the patients.
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http://dx.doi.org/10.12122/j.issn.1673-4254.2020.03.01 | DOI Listing |
Int J Biomed Imaging
January 2025
Medical Imaging Sciences Department, College of Health Sciences, Gulf Medical University, Ajman, UAE.
The quality of CT images obtained from hepatocellular carcinoma (HCC) patients is complex, affecting diagnostic accuracy, precision, and radiation dose assessment due to increased exposure risks. The study evaluated image quality qualitatively and quantitatively by comparing quality levels with an effective radiation dose to ensure acceptable quality accuracy. This study retrospectively reviewed 100 known HCC patients (Li-RADS-5) who underwent multidetector computed tomography (MDCT) multiphasic scans for follow-up of their health condition between January and October 2023.
View Article and Find Full Text PDFPlasma protein levels provide important insights into human disease, yet a comprehensive assessment of plasma proteomics across organs is lacking. Using large-scale multimodal data from the UK Biobank, we integrated plasma proteomics with organ imaging to map their phenotypic and genetic links, analyzing 2,923 proteins and 1,051 imaging traits across multiple organs. We uncovered 5,067 phenotypic protein-imaging associations, identifying both organ-specific and organ-shared proteomic relations, along with their enriched protein-protein interaction networks and biological pathways.
View Article and Find Full Text PDFCureus
December 2024
Pulmonology, Algemeen Ziekenhuis Glorieux, Ronse, BEL.
Heterotaxy syndrome is characterized by abnormal left-right arrangement of thoracoabdominal organs and is frequently associated with complex cardiac anomalies. However, cases with predominant extracardiac manifestations are increasingly recognized. This report describes a 20-year-old female of North African descent with consanguineous parentage, who presented with chronic cough and exertional dyspnea persisting over several years.
View Article and Find Full Text PDFHeliyon
January 2025
Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, Xinjiang, 830046, China.
Statins are widely used for treating lipid disorders and cardiovascular diseases. However, the therapeutic efficiency and adverse effects of statins vary among different patients, which numerous clinical and epidemiological studies have attributed to genetic polymorphisms in statin-metabolizing enzymes and transport proteins. The metabolic processes of statins are relatively complex, involving spontaneous or enzyme-catalyzed interconversion between more toxic lactone metabolites and active acid forms in the liver and bloodstream, influenced by multiple factors, including the expression levels of many metabolic enzymes and transporters.
View Article and Find Full Text PDFAME Case Rep
November 2024
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.
Background: Pulmonary epithelioid hemangioendothelioma (P-EHE) is a rare vascular tumor derived from mesenchymal cells with an incidence of about 1/1 million. The etiology remains unclear, and there are no established treatment guidelines. The tumor can occur in a variety of organs, among which the liver, lung and bone are the most commonly involved, with different clinical manifestations, mainly depending on the organ involved, but none of them is specific.
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