AI Article Synopsis
- Carbapenem resistance is a significant concern, particularly regarding NDM-producing enterobacterial strains in West Africa.
- This study focused on identifying carbapenemase-producing clinical strains from Bamako Teaching Hospital in Mali, examining 50 isolates collected over a few months in 2016.
- The research successfully identified the first instance of NDM-5 in Mali, revealing a new strain type (ST448) associated with a specific plasmid (IncX3).
Article Abstract
Carbapenem resistance in has become an increasingly worrying threat. So far, no epidemiological data regarding NDM-producing enterobacterial isolates has been available on these strains in West Africa. The aim of this study was to seek for carbapenemase-producing clinical strains isolated in Bamako Teaching Hospital in Mali. Of 50 strains isolated between May 2016 and September 2016, we found a ST448 harbouring an IncX3 plasmid with embedded in the Δ structure. This study reports the first description of NDM-5 in Mali isolated in an undescribed ST in West Africa.
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