AI Article Synopsis
- COVID-19 is a global pandemic that has impacted over 200 countries, with the U.S. reporting around 180,000 cases and exceeding fatalities seen in China and Italy.
- The disease primarily affects the respiratory system, but emerging data indicates that the virus can also cause acute kidney injury, which is linked to poorer outcomes and higher mortality rates.
- A case study highlights a COVID-19 patient whose rapid decline in kidney function coincided with worsening health, suggesting that monitoring kidney health could be crucial for assessing risks in critically ill patients.
Article Abstract
Coronavirus disease 2019 (COVID-19) is a global pandemic affecting more than 200 countries and 180,000 cases in the United States. While the outbreak began in China, the number of cases outside of China exceeded those in China on March 15, 2020 and are currently rising at an exponential rate. The number of fatalities in the United States are expected to exceed more than Italy and China. The disease is characterized predominantly as an acute respiratory illness. However, preliminary data suggests that kidney is a target for the virus and deterioration of renal function was associated with poor outcomes including in-hospital mortality. We pre-sent a report of a patient with COVID-19 who presented with acute onset of symptoms and normal renal function at baseline but rapidly deteriorated resulting in death. The timing of decline in renal function correlated with his worsening clinical status. He was started on continuous veno-venous hemofiltration without signs of clinical benefit. We also present the possible mechanisms for acute kidney injury in these patients. We performed a review of the emerging literature by searching PubMed, Google Scholar, and EMBASE for studies and/or case series published on this topic. Acute kidney injury might help risk stratify critically ill patients on a fatal course of COVID-19.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251584 | PMC |
| http://dx.doi.org/10.1159/000508179 | DOI Listing |
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