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Maternal microchimerism protects hemophilia A patients from inhibitor development. | LitMetric

Deleterious mutations do not necessarily lead to the incidence of inhibitors in hemophilia A patients receiving replacement therapy. Maternal chimeric cells migrated into a fetus with hemophilia A during pregnancy could induce tolerance toward FVIII.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218421PMC
http://dx.doi.org/10.1182/bloodadvances.2020001832DOI Listing

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