Designing reactions in aqueous media has been one of the major challenges in modern organic synthesis, especially to avoid the use of large amounts of organic solvents whose disposal is a matter of grave concern from an environmental perspective. The oxidation of alcohols and amines is an essential and important step in the synthesis of many valuable products including polymers and pharmaceuticals. In recent times, there has been a surge in the use of water as a solvent in many organic reactions. This review focuses specifically on the oxidation reactions of alcohols and amines carried out in water media using transition metal catalysts, metal-free catalysts and photocatalysts.

Download full-text PDF

Source
http://dx.doi.org/10.1002/asia.202000299DOI Listing

Publication Analysis

Top Keywords

alcohols amines
12
oxidation alcohols
8
water solvent
8
catalytic oxidation
4
amines value-added
4
value-added chemicals
4
chemicals water
4
solvent designing
4
designing reactions
4
reactions aqueous
4

Similar Publications

Ketamine HCl, an FDA-approved therapeutic, is administered through various routes, including intranasal delivery. Administering an adequate therapeutic dose of intranasal ketamine HCl is challenging due to the limited volume that can be delivered intranasally given the current commercially available concentrations. This study investigates solubilizing strategies to enhance the aqueous solubility of ketamine HCl for intranasal administration.

View Article and Find Full Text PDF

Menopause leads to a decline in estrogen levels, resulting in significant metabolic alterations that increase the risk of developing metabolic syndrome-a cluster of conditions including central obesity, insulin resistance, dyslipidemia, and hypertension. Traditional interventions such as hormone replacement therapy carry potential adverse effects, and lifestyle modifications alone may not suffice for all women. This review explores the potential role of palmitoylethanolamide (PEA), an endogenous fatty acid amide, in managing metabolic syndrome during the postmenopausal period.

View Article and Find Full Text PDF

Polymerizable Cholinium-Based Antibiotics for Polymer Carriers: Systems with Combined Load of Cloxacillin and Ampicillin.

Molecules

December 2024

Department of Physical Chemistry and Technology of Polymers, Faculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.

Single and dual-drug delivery systems (DDSs) based on linear choline polymers were designed through the controlled polymerization of a pharmaceutically functionalized monomer, i.e., [2-(methacryloyloxy)ethyl]trimethylammonium, with counterions of cloxacillin (TMAMA/CLX), or its copolymerization with [2-(methacryloyloxy)ethyl]trimethylammonium with ampicillin (TMAMA/AMP), providing antibiotic properties.

View Article and Find Full Text PDF

The aim of this study was to assess the impact of tomato pomace (TP) on the content of volatile compounds and L-carnitine and the sensory characteristics of raw fermented sausages produced with reduced nitrite. The produced sausages were divided into three experimental groups: control sample, sample with 1.5% addition of freeze-dried tomato pomace, and sample with 2.

View Article and Find Full Text PDF

Retrotransposon Gag-like 4 (), a gene acquired from a retrovirus, is a causative gene in autism spectrum disorder. Its knockout mice exhibit increased impulsivity, impaired short-term spatial memory, failure to adapt to novel environments, and delayed noradrenaline (NA) recovery in the frontal cortex. However, due to its very low expression in the brain, it remains unknown which brain cells express RTL4 and its dynamics in relation to NA.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!