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| http://dx.doi.org/10.3389/fimmu.2020.00811 | DOI Listing |
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Commentary on "Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth".
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Molecular Epidemiology (MOLE), Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
VTRNA2-1 is a polymorphically imprinted locus. The proportion of individuals with a maternally imprinted VTRNA2-1 locus is consistently approximately 75% in populations of European origin, with the remaining circa 25% having a non-methylated VTRNA2-1 locus. Recently, VTRNA2-1 hypermethylation at birth was suggested to be a precursor of paediatric acute lymphoblastic leukaemia with biomarker potential.
View Article and Find Full Text PDFLateral epicondylitis is a common cause of elbow pain and disability, resulting from degenerative tendinosis of the extensor carpi radialis brevis origin at the lateral epicondyle. This condition is generally self-limiting, with activity modification, physical therapy, and injections serving as the first-line treatments. Surgery is typically reserved for patients experiencing ongoing pain and disability that impact daily living or recreational activities, despite extensive conservative management for at least 6 months, ideally over 12 months.
View Article and Find Full Text PDFLimited evidence that fitness interdependence produces historical origin myths.
Behav Brain Sci
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Department of Sociology, Columbia University, New York, NY,
This commentary points out some theoretical lacuna in the argument and then evaluates, in a preliminary way, its main comparative empirical hypotheses. It finds very limited support for the observable implications of the evolutionary theory. By contrast, the historical remoteness of foundational myths is closely associated with how long a society has been ruled by a centralized state, pointing at the important role of political history.
View Article and Find Full Text PDFQuantifying the genetic origins of body plan scaling.
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AMOLF, Amsterdam 1098 XG, The Netherlands.
Anisogamy and sex roles: a commentary.
Evol Lett
December 2024
Department of Life Sciences, Milner Centre for Evolution, University of Bath, Bath BA2 7AY, United Kingdom.
The origin and maintenance of sex differences in reproductive behavior (often labeled sex roles) have remained controversial topics, and recent meta-analyses and theoretical models have helped to elucidate the processes that generate diverse sex roles. We are glad to see that our study (Mokos et al., 2021) generated a healthy debate, and in agreement with recent commentaries (Janicke, 2024; Lehtonen & Parker, 2024) we call for a more comprehensive approach to understanding sex role evolution.
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