AI Article Synopsis
- The study aimed to evaluate the effectiveness of epidermal vacuum wound dressings compared to conventional wound care in patients undergoing inguinal lymphadenectomy for penile cancer.
- A total of 31 patients were involved, with results showing no significant differences in fluid drainage, complication rates, or hospital stays between the two treatment methods.
- The findings suggest that both approaches yield similar outcomes, indicating that the vacuum dressing may not provide additional benefits over conventional methods in this patient population.
Article Abstract
Purpose: Inguinal lymphadenectomy in penile cancer is associated with a high rate of wound complications. The aim of this trial was to prospectively analyze the effect of an epidermal vacuum wound dressing on lymphorrhea, complications and reintervention in patients with inguinal lymphadenectomy for penile cancer.
Patients And Methods: Prospective, multicenter, randomized, investigator-initiated study in two German university hospitals (2013-2017). Thirty-one patients with penile cancer and indication for bilateral inguinal lymph node dissection were included and randomized to conventional wound care on one side (CONV) versus epidermal vacuum wound dressing (VAC) on the other side.
Results: A smaller cumulative drainage fluid volume until day 14 (CDF) compared to contralateral side was observed in 15 patients (CONV) vs. 16 patients (VAC), with a median CDF 230 ml (CONV) vs. 415 ml (VAC) and a median maximum daily fluid volume (MDFV) of 80 ml (CONV) vs. 110 ml (VAC). Median time of indwelling drainage: 7 days (CONV) vs. 8 days (VAC). All grade surgery-related complications were seen in 74% patients (CONV) vs. 74% patients (VAC); grade 3 complications in 3 patients (CONV) vs. 6 patients (VAC). Prolonged hospital stay occurred in 32% patients (CONV) vs. 48% patients (VAC); median hospital stay was 11.5 days. Reintervention due to complications occurred in 45% patients (CONV) vs. 42% patients (VAC).
Conclusions: In this prospective, randomized trial we could not observe a significant difference between epidermal vacuum treatment and conventional wound care.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910363 | PMC |
| http://dx.doi.org/10.1007/s00345-020-03221-z | DOI Listing |
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